{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T17:50:28Z","timestamp":1791827428482,"version":"4.3.4"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T00:00:00Z","timestamp":1230508800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2009,9]]},"abstract":"<jats:p><jats:bold>Abstract:\u2002<\/jats:bold> In the first two\u2003yr of life blood\u2010group incompatible (ABO\u2010incompatible) heart transplantation can be performed leading to immune tolerance to donor blood group. Antibody titers should be below 1:4. VAD use is correlated with sensitization toward blood\u2010group antigens. A boy was diagnosed with dilated cardiomyopathy at nine months of age and listed for 0\u2010compatible transplantation. Progressive heart failure required implantation of a left VAD. His listing was extended for ABO\u2010incompatible transplantation despite antibody titers of 1:32 anti\u2010A and 1:8 anti\u2010B. After 26\u2003days on VAD, he was transplanted with a B donor heart. No hyperacute or acute rejection occurred in 12\u2003months post\u2010transplant. Anti\u2010B antibodies rose to a maximum of 1:2. No use of rituximab or plasmapheresis was required. There are no signs of graft vasculopathy. This indicates that inclusion criteria for ABO\u2010incompatible transplantation may be extended to immediate cases. This is the first case with a healthy immune system to show signs of tolerance development after ABO\u2010incompatible heart transplantation with increased prior antibody titers and without specific treatment.<\/jats:p>","DOI":"10.1111\/j.1399-3046.2008.01030.x","type":"journal-article","created":{"date-parts":[[2008,12,31]],"date-time":"2008-12-31T17:36:54Z","timestamp":1230745014000},"page":"773-776","source":"Crossref","is-referenced-by-count":8,"title":["Successful ABO\u2010incompatible heart transplantation in a child despite blood\u2010group sensitization after ventricular assist device support"],"prefix":"10.1111","volume":"13","author":[{"given":"S.","family":"Urschel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Dalla Pozza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Loeff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Schmitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Sodian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Schmoeckel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Kowalski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Netz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,8,7]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2004.00364.x"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000136263.46262.0D"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2004.05.038"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200103153441102"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mot.0000188316.19534.3c"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000203829.78700.f3"},{"key":"e_1_2_6_8_2","volume-title":"Report of the OPTN\/UNOS Pediatric Transplantation Commitee to the Board of Directors","author":"Sweet S","year":"2008"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1067\/mtc.2003.30"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3083.2005.01584.x"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/76882"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5699(82)90095-0"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.7.2740"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm1126"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2005.09.048"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2007.01780.x"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2007.02040.x"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-3046.2008.01030.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-3046.2008.01030.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T15:01:04Z","timestamp":1696950064000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-3046.2008.01030.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,8,7]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,9]]}},"alternative-id":["10.1111\/j.1399-3046.2008.01030.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-3046.2008.01030.x","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,8,7]]}}}