{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,2,27]],"date-time":"2024-02-27T17:02:17Z","timestamp":1709053337217},"reference-count":26,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T00:00:00Z","timestamp":1230508800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2009,11]]},"abstract":"<jats:p><jats:bold>Abstract:\u2002<\/jats:bold> UTI are common in renal Tx recipients and may significantly impact on the graft function. The aim of our study was to evaluate the prevalence, risk factors, and significance of UTI in Tx children. We performed a retrospective cross\u2010sectional study of 76 Tx patients, median age at Tx was 13.4\u2003yr. Twenty\u2010one of 76 (28%) patients developed at least one UTI during the mean follow\u2010up time of 3.3\u2003\u00b1\u20032.0\u2003yr post\u2010Tx. The first UTI occurred at a median of 160\u2003days post\u2010Tx. The RR of having UTI was significantly higher in patients with the primary diagnosis of obstructive uropathy (RR\u2003=\u20032.6, 95th CI\u2003= 1.1\u20136.0, p\u2003=\u20030.032), history of PN pre Tx (RR\u2003=\u20032.7, 95th CI\u2003= 1.3\u20135.4, p\u2003=\u20030.009) and pre Tx VUR (RR\u2003=\u20032.2, 95th CI\u2003=\u20031.1\u20134.5, p\u2003=\u20030.045). These three factors also significantly decreased the infection\u2010free survival time to the first UTI. Most UTI caused reversible acute allograft dysfunction, but the long\u2010term graft function could not be reliably assessed with SCr. In conclusion, UTI occurred in 28% of pediatric Tx recipients, mostly during the first year post\u2010Tx despite antibiotic prophylaxis. The diagnosis of obstructive uropathy, history of UTI and VUR prior to Tx were significant risk factors.<\/jats:p>","DOI":"10.1111\/j.1399-3046.2008.01079.x","type":"journal-article","created":{"date-parts":[[2008,12,31]],"date-time":"2008-12-31T17:36:54Z","timestamp":1230745014000},"page":"881-886","source":"Crossref","is-referenced-by-count":9,"title":["Urinary tract infections in pediatric renal transplant recipients \u2013 a two center risk factors 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