{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T13:03:10Z","timestamp":1784034190404,"version":"3.55.0"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,2,15]],"date-time":"2011-02-15T00:00:00Z","timestamp":1297728000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:p>Acikgoz Y, Ozkaya O, Bek K, Genc G, Sensoy SG, Hokelek M. Cryptosporidiosis: A rare and severe infection in a pediatric renal transplant recipient.<\/jats:p><jats:p><jats:bold>Abstract:\u2002<\/jats:bold> Cryptosporidium is an intracellular protozoan parasite that causes gastroenteritis in human. In immunocompromised individuals, cryptosporidium causes far more serious disease. There is no effective specific therapy for cryptosporidiosis, and spontaneous recovery is the rule in healthy individuals. However, immunocompromised patients need effective and prolonged therapy. Here, we present our clinical experience in a six\u2010yr\u2010old boy who underwent living\u2010related donor renal transplantation and who was infected with Cryptosporidium spp. Our patient was successfully treated with antimicrobial agents consisting of spiramycin, nitazoxanide, and paromomycin. At the end of second week of therapy, his stool became negative for Cryptosporidium spp. antigen and spiramycin was discontinued. Nitazoxanide and paromomycin treatment was extended to four\u2003wk. With this case, we want to emphasize that cryptosporidiosis should be considered in the differential diagnosis of severe or persistent diarrhea in solid organ transplant recipients where rigorous antimicrobial therapy is needed.<\/jats:p>","DOI":"10.1111\/j.1399-3046.2011.01473.x","type":"journal-article","created":{"date-parts":[[2011,2,15]],"date-time":"2011-02-15T10:53:15Z","timestamp":1297767195000},"source":"Crossref","is-referenced-by-count":16,"title":["Cryptosporidiosis: A rare and severe infection in a pediatric renal transplant recipient"],"prefix":"10.1111","volume":"16","author":[{"given":"Yonca","family":"Acikgoz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ozan","family":"Ozkaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenan","family":"Bek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gurkan","family":"Genc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sema Gulnar","family":"Sensoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Hokelek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,2,15]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.3109\/10408418809104469"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.50.4.458-483.1986"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.15.1.145-154.2002"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2007.00237.x"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3046.2000.00087.x"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2006.00593.x"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0012.2001.00002.x"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2008.02.007"},{"key":"e_1_2_5_10_2","volume-title":"Water\u2010borne Disease: Epidemiology and Ecology","author":"Hunter PR","year":"1997"},{"key":"e_1_2_5_11_2","first-page":"813","article-title":"Cryptosporidiosis in HIV\u2010seropositive patients","volume":"85","author":"Blanshard C","year":"1992","journal-title":"Q J Med"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-009-1274-y"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2004.08.107"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)91478-S"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/160.3.559"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004310050023"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/165.4.772"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(02)03278-5"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2008.04.010"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1053\/rvsc.1998.0239"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2005.00315.x"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-3046.2011.01473.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-3046.2011.01473.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T01:42:30Z","timestamp":1698630150000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-3046.2011.01473.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,2,15]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["10.1111\/j.1399-3046.2011.01473.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-3046.2011.01473.x","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,2,15]]}}}