{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,15]],"date-time":"2025-03-15T04:25:16Z","timestamp":1742012716015,"version":"3.38.0"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,11,29]],"date-time":"2011-11-29T00:00:00Z","timestamp":1322524800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:p>Filler G, Liu D, Sharma AP, Grimmer J. Are fibroblast growth factor 23 concentrations in renal transplant patients different from non\u2010transplanted chronic kidney disease patients? \u2028Pediatr Transplantation 2012: 16: 73\u201377. \u00a9 2011 John Wiley &amp; Sons A\/S.<\/jats:p><jats:p><jats:bold>Abstract:\u2002<\/jats:bold>To compare the pattern of serum FGF23 levels in pediatric renal transplant recipients and GFR\u2010matched controls. We performed a cross\u2010sectional matched pair study in 19 stable pediatric renal transplant recipients and 19 GFR\u2010matched controls with native CKD. After assessment for normal distribution, demographic and bone metabolism parameters were compared with Student\u2019s<jats:italic>t<\/jats:italic>\u2010test, Wilcoxon\u2019s matched pairs (for non\u2010normal distribution) test, and correlation analysis. The groups were comparable for anthropometric parameters, cystatin C eGFR (71.10\u2003\u00b1\u200337.28 vs. 76.11\u2003\u00b1\u200326.80\u2003mL\/min\/1.73\u2003m<jats:sup>2<\/jats:sup>), cystatin C, urea, creatinine, intact PTH, pH, CRP, alkaline phosphatase, phosphate, calcium, ionized calcium, FGF\u201023 (63.44 [IQR 38.42, 76.29], 49.92 [IQR 42.48, 76.97]), albumin, and urinary calcium\/creatinine ratio. The renal transplant patients had significantly lower 25\u2010(OH) vitamin D levels (66.63\u2003\u00b1\u200317.54 vs. 91.42\u2003\u00b1\u200329.16\u2003ng\/mL), and higher 1,25\u2010(OH)<jats:sub>2<\/jats:sub>vitamin D levels (95.78\u2003\u00b1\u200334.54 vs. 67.11\u2003\u00b1\u200335.90\u2003p<jats:sc>m<\/jats:sc>). FGF\u201023 levels correlated negatively with cystatin C eGFR (<jats:italic>r<\/jats:italic>\u2003=\u2003\u22120.3571, p\u2003=\u20030.02770) and positively with PTH (<jats:italic>r<\/jats:italic>\u2003=\u20030.5063, p\u2003=\u20030.0026), but not with serum phosphate (<jats:italic>r<\/jats:italic>\u2003=\u20030.2651, p\u2003=\u20030.1077). We conclude that the increase in FGF23 levels with GFR decline in pediatric renal transplant patients remains similar to that in the patients with CKD. The relationship between FGF23 and serum vitamin D needs further evaluation.<\/jats:p>","DOI":"10.1111\/j.1399-3046.2011.01613.x","type":"journal-article","created":{"date-parts":[[2011,11,30]],"date-time":"2011-11-30T13:31:10Z","timestamp":1322659870000},"page":"73-77","source":"Crossref","is-referenced-by-count":8,"title":["Are fibroblast growth factor 23 concentrations in renal transplant patients different from non\u2010transplanted chronic kidney disease patients?"],"prefix":"10.1111","volume":"16","author":[{"given":"Guido","family":"Filler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisy","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ajay Parkash","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanne","family":"Grimmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,11,29]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2007.00782.x"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-010-1382-5"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfr126"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2010080894"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-10-1150"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2007.01753.x"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5001788"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.01310308"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-1576"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2004.09.025"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1159\/000105138"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2011.01.009"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-139x.2001.00014.x"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-021105"},{"key":"e_1_2_6_16_2","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1093\/clinchem\/43.6.1077","article-title":"Are cystatin C and beta 2\u2010microglobulin better markers than serum creatinine for prediction of a normal glomerular filtration rate in pediatric subjects?","volume":"43","author":"Filler G","year":"1997","journal-title":"Clin Chem"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.58.2.259"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1159\/000093277"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfq777"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.06040710"},{"key":"e_1_2_6_21_2","doi-asserted-by":"crossref","first-page":"300","DOI":"10.20452\/pamw.953","article-title":"KDIGO clinical practice guidelines for the diagnosis, evaluation, prevention, and treatment of mineral and bone disorders in chronic kidney disease","volume":"120","author":"Matuszkiewicz\u2010Rowinska J","year":"2010","journal-title":"Pol Arch Med Wewn"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-3046.2011.01613.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-3046.2011.01613.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T16:46:09Z","timestamp":1741970769000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-3046.2011.01613.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11,29]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["10.1111\/j.1399-3046.2011.01613.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-3046.2011.01613.x","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"type":"print","value":"1397-3142"},{"type":"electronic","value":"1399-3046"}],"subject":[],"published":{"date-parts":[[2011,11,29]]}}}