{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T14:30:21Z","timestamp":1705588221425},"reference-count":38,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,6,4]],"date-time":"2012-06-04T00:00:00Z","timestamp":1338768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:p>Karnsakul W, Intihar P, Konewko R, Roy A, Colombani PM, Lau H, Schwarz KB. Living donor liver transplantation in children: A single North American center experience over two decades.<\/jats:p><jats:p><jats:bold>Abstract:\u2002<\/jats:bold> Little data concerning hospital charges and long\u2010term outcomes of LDLT in North American children according to transplant indications have been published. To compare outcomes of patient and graft survival and healthcare charges for LDLT for those with BA vs. other diagnoses (non\u2010BA). A retrospective review of 52 children receiving 53 LDLT (38 BA and 14 non\u2010BA) from 1992 to 2010 at our institution was performed. One\u2010, five\u2010, and 10\u2010yr patient and graft survival data were comparable to national figures reported to UNOS. Average one\u2010yr charges for recipients and donors were $242\u2003849 for BA patients and $183\u2003614 for non\u2010BA (p\u2003=\u20030.074). BA patients were 1.23\u2003\u00b1\u20031.20\u2003yr of age vs. 4.25\u2003\u00b1\u20035.02 for non\u2010BA, p\u2003=\u20030.045. Examination of the total population of patients who were alive in 2010 in five chronological groupings showed that the crude five\u2010yr survival rates were 1992\u20131995: 9\/11 (82%); 1995\u20131997: 6\/10 (60%); 1997\u20131999: 8\/10 (80%); 1999\u20132001: 9\/10 (90%); and 2001\u20132003: 7\/7 (100%). Thus, examination of the clinical and financial data together over the entire period of the transplant program suggests that the dramatic improvement in patient survival was accomplished without a dramatic increase in indexed charges. All 53 donors survived, and only 10% had complications requiring hospitalization. LDLT in children results in excellent outcomes for patients and donors. Ways to lower costs and maximize graft outcome should be investigated.<\/jats:p>","DOI":"10.1111\/j.1399-3046.2012.01725.x","type":"journal-article","created":{"date-parts":[[2012,6,4]],"date-time":"2012-06-04T18:46:51Z","timestamp":1338835611000},"page":"486-495","source":"Crossref","is-referenced-by-count":9,"title":["Living donor liver transplantation in children: A single North American center experience over two decades"],"prefix":"10.1111","volume":"16","author":[{"given":"W.","family":"Karnsakul","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Intihar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Konewko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Roy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. M.","family":"Colombani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Lau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. B.","family":"Schwarz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,6,4]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199110000-00007"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199304000-00029"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(91)90989-7"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-200007000-00015"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3046.2001.00055.x"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(00)80004-4"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2006.01626.x"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1053\/jlts.2000.18686"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3181aaccb0"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000046534.45645.47"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/lt.20663"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/lt.20650"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3046.2002.1r058.x"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2001.115068"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2004.03.032"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800600817"},{"key":"e_1_2_8_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2008.11.014"},{"key":"e_1_2_8_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2010.11.013"},{"key":"e_1_2_8_20_2","doi-asserted-by":"publisher","DOI":"10.1053\/jlts.2001.27963"},{"key":"e_1_2_8_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e318196c379"},{"key":"e_1_2_8_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199901270-00024"},{"key":"e_1_2_8_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-002-6598-8"},{"key":"e_1_2_8_24_2","first-page":"355","article-title":"Experience with living related liver transplantation in 63 children","volume":"62","author":"Otte JB","year":"1999","journal-title":"Acta Gastroenterol Belg"},{"key":"e_1_2_8_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(98)01671-6"},{"key":"e_1_2_8_26_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004230050239"},{"key":"e_1_2_8_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(00)01613-4"},{"key":"e_1_2_8_28_2","doi-asserted-by":"publisher","DOI":"10.1002\/lt.500040211"},{"key":"e_1_2_8_29_2","first-page":"315","article-title":"Preoperative predictors of resource utilization in liver transplantation","volume":"53","author":"Kim WR","year":"1995","journal-title":"Clin Transpl"},{"key":"e_1_2_8_30_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.281.15.1381"},{"key":"e_1_2_8_31_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-006-1887-x"},{"key":"e_1_2_8_32_2","first-page":"283","article-title":"Reducing the cost of marginal organ utilization: Is there a national learning curve?","volume":"7","author":"Axelrod DA","year":"2007","journal-title":"Am J Transplant"},{"key":"e_1_2_8_33_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840160527"},{"key":"e_1_2_8_34_2","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2001.21489"},{"key":"e_1_2_8_35_2","first-page":"4","article-title":"Organ transplantation legislation takes a tortuous path through Congress","volume":"1","author":"Dennis L","year":"2000","journal-title":"AASLD News"},{"key":"e_1_2_8_36_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2010.01356.x"},{"key":"e_1_2_8_37_2","doi-asserted-by":"publisher","DOI":"10.1002\/lt.22388"},{"key":"e_1_2_8_38_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.2014"},{"key":"e_1_2_8_39_2","doi-asserted-by":"publisher","DOI":"10.1002\/lt.22342"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-3046.2012.01725.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-3046.2012.01725.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T02:35:21Z","timestamp":1698633321000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-3046.2012.01725.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6,4]]},"references-count":38,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["10.1111\/j.1399-3046.2012.01725.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-3046.2012.01725.x","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6,4]]}}}