{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T10:59:31Z","timestamp":1789901971612,"version":"4.0.1"},"reference-count":52,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,7,12]],"date-time":"2012-07-12T00:00:00Z","timestamp":1342051200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiologia Plantarum"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:p><jats:styled-content style=\"fixed-case\"><jats:italic>NPR1<\/jats:italic><\/jats:styled-content> (a non\u2010expressor of pathogenesis\u2010related genes1) has been reported to play an important role in plant defense by regulating signaling pathways. However, little to nothing is known about its function in herbivore\u2010induced defense in monocot plants. Here, using suppressive substrate hybridization, we identified a <jats:styled-content style=\"fixed-case\"><jats:italic>NPR1<\/jats:italic><\/jats:styled-content> gene from rice, <jats:italic><jats:styled-content style=\"fixed-case\">OsNPR1<\/jats:styled-content><\/jats:italic>, and found that its expression levels were upregulated in response to infestation by the rice striped stem borer (<jats:styled-content style=\"fixed-case\">SSB<\/jats:styled-content>) <jats:italic>Chilo suppressalis<\/jats:italic> and rice leaf folder  (<jats:styled-content style=\"fixed-case\">LF<\/jats:styled-content>) <jats:italic>Cnaphalocrocis medinalis<\/jats:italic>, and to mechanical wounding and treatment with jasmonic acid (<jats:styled-content style=\"fixed-case\">JA<\/jats:styled-content>) and salicylic acid  (<jats:styled-content style=\"fixed-case\">SA<\/jats:styled-content>). Moreover, mechanical wounding induced the expression of <jats:italic><jats:styled-content style=\"fixed-case\">OsNPR1<\/jats:styled-content><\/jats:italic> quickly, whereas herbivore infestation induced the gene more slowly. The antisense expression of <jats:italic><jats:styled-content style=\"fixed-case\">OsNPR1<\/jats:styled-content><\/jats:italic> (as\u2010<jats:italic>npr1<\/jats:italic>), which reduced the expression of the gene by 50%, increased elicited levels of <jats:styled-content style=\"fixed-case\">JA<\/jats:styled-content> and ethylene (<jats:styled-content style=\"fixed-case\">ET<\/jats:styled-content>) as well as of expression of a lipoxygenase gene <jats:italic><jats:styled-content style=\"fixed-case\">OsHI\u2010LOX<\/jats:styled-content><\/jats:italic> and an <jats:styled-content style=\"fixed-case\">ACC<\/jats:styled-content> synthase gene <jats:italic><jats:styled-content style=\"fixed-case\">OsACS2<\/jats:styled-content><\/jats:italic>. The enhanced <jats:styled-content style=\"fixed-case\">JA<\/jats:styled-content> and ET signaling in as\u2010<jats:italic>npr1<\/jats:italic> plants increased the levels of herbivore\u2010induced trypsin proteinase inhibitors (<jats:styled-content style=\"fixed-case\">TrypPIs<\/jats:styled-content>) and volatiles, and reduced the performance of <jats:styled-content style=\"fixed-case\">SSB<\/jats:styled-content>. Our results suggest that <jats:italic><jats:styled-content style=\"fixed-case\">OsNPR1<\/jats:styled-content><\/jats:italic> is an early responding gene in herbivore\u2010induced defense and that plants can use it to activate a specific and appropriate defense response against invaders by modulating signaling pathways.<\/jats:p>","DOI":"10.1111\/j.1399-3054.2012.01666.x","type":"journal-article","created":{"date-parts":[[2012,6,13]],"date-time":"2012-06-13T17:19:38Z","timestamp":1339607978000},"page":"340-351","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["<i><scp>OsNPR1<\/scp><\/i> negatively regulates herbivore\u2010induced <scp>JA<\/scp> and ethylene signaling and plant resistance to a chewing herbivore in rice"],"prefix":"10.1111","volume":"147","author":[{"given":"Ran","family":"Li","sequence":"first","affiliation":[{"name":"State Key Laboratory of Rice Biology Institute of Insect Sciences Zhejiang 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