{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T10:28:12Z","timestamp":1790677692103,"version":"4.1.0"},"reference-count":7,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,9,12]],"date-time":"2006-09-12T00:00:00Z","timestamp":1158019200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2006,12]]},"abstract":"<jats:p><jats:bold>Abstract: <\/jats:bold> False\u2010positive <jats:italic>Histoplasma<\/jats:italic> antigenemia was reported in solid organ allograft recipients who had received rabbit anti\u2010thymocyte globulin (RATG, RATG<jats:sup>\u00ae<\/jats:sup>) caused by human anti\u2010rabbit antibodies (HARA). A second\u2010generation <jats:italic>Histoplasma<\/jats:italic> antigen detection assay was developed to overcome false positivity caused by HARA. With the second\u2010generation assay, false\u2010positive results were eliminated in 18 of 19 cases without reduction in the sensitivity in patients with histoplasmosis. In fact, sensitivity for detection of antigenuria in patients with acquired immunodeficiency syndrome and disseminated histoplasmosis was higher in the second\u2010generation assay. Physicians should be aware of the potential for false\u2010positive results in sandwich immunoassays in specimens from patients who have received RATG.<\/jats:p>","DOI":"10.1111\/j.1399-3062.2006.00151.x","type":"journal-article","created":{"date-parts":[[2006,9,12]],"date-time":"2006-09-12T14:19:48Z","timestamp":1158070788000},"page":"219-221","source":"Crossref","is-referenced-by-count":29,"title":["Elimination of false\u2010positive <i>Histoplasma<\/i> antigenemia caused by human anti\u2010rabbit antibodies in the second\u2010generation <i>Histoplasma<\/i> antigen assay"],"prefix":"10.1111","volume":"8","author":[{"given":"L.J.","family":"Wheat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Connolly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Durkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.K.","family":"Book","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.D.","family":"Pescovitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,9,12]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2004.00045.x"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/45.7.942"},{"key":"e_1_2_5_4_2","doi-asserted-by":"crossref","first-page":"2252","DOI":"10.1128\/jcm.35.9.2252-2255.1997","article-title":"Comparison of radioimmunoassay and enzyme\u2010linked immunoassay methods for detection of Histoplasma capsulatum var. capsulatum antigen","volume":"35","author":"Durkin MM","year":"1997","journal-title":"J Clin Microbiol"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(97)00151-4"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/36.6.892"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2003.08.007"},{"key":"e_1_2_5_8_2","first-page":"129","article-title":"Pulmonary histoplasmosis syndromes","volume":"25","author":"Wheat LJ","year":"2004","journal-title":"recognition, diagnosis, and management"}],"container-title":["Transplant Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-3062.2006.00151.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-3062.2006.00151.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T15:08:14Z","timestamp":1696950494000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-3062.2006.00151.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,9,12]]},"references-count":7,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["10.1111\/j.1399-3062.2006.00151.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-3062.2006.00151.x","archive":["Portico"],"relation":{},"ISSN":["1398-2273","1399-3062"],"issn-type":[{"value":"1398-2273","type":"print"},{"value":"1399-3062","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,9,12]]}}}