{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T16:30:39Z","timestamp":1790094639971,"version":"4.0.1"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2007,2,21]],"date-time":"2007-02-21T00:00:00Z","timestamp":1172016000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2007,3]]},"abstract":"<jats:p><jats:bold>Abstract: <\/jats:bold> Only localized cases of <jats:italic>Mycobacterium chelonae<\/jats:italic> osteomyelitis have been reported. In this article, a 55\u2010year\u2010old immunosuppressed man with <jats:italic>M. chelonae<\/jats:italic> osteomyelitis and multiple spinal and extra\u2010spinal involvement is presented. The patient had nodulo\u2010pustular skin lesions, spondylodiscitis at multiple levels, and osteolytic lesions at extra\u2010spinal locations. Biopsy and cultures of the osseous lesions showed <jats:italic>M. chelonae<\/jats:italic> osteomyelitis. The patient started antimycobacterial chemotherapy with ciprofloxacin and clarithromycin. Progressive cervical kyphosis associated with anterior wedged deformity of the C5 vertebra and posterior C5\u2013C6 spondylolisthesis resulted in compression of the spinal cord and neurological impairment. The patient underwent anterior decompression and C4\u2013C6 arthrodesis using a titanium mesh cage and cervical plate. About 15 months after the initiation of chemotherapy and 5 months after surgery, the patient was pain free, with significant improvement of his neurological function. In the presence of immunosuppression, the physician should be alert for unusual or opportunistic pathogens of osteomyelitis. Long\u2010term antimicrobial chemotherapy and surgical intervention is the cornerstone of successful treatment of multifocal bone <jats:italic>M. chelonae<\/jats:italic> infection.<\/jats:p>","DOI":"10.1111\/j.1399-3062.2006.00178.x","type":"journal-article","created":{"date-parts":[[2007,2,21]],"date-time":"2007-02-21T13:32:46Z","timestamp":1172064766000},"page":"62-65","source":"Crossref","is-referenced-by-count":25,"title":["Multifocal spinal and extra\u2010spinal <i>Mycobacterium chelonae<\/i> osteomyelitis in a renal transplant recipient"],"prefix":"10.1111","volume":"9","author":[{"given":"D.S.","family":"Korres","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.J.","family":"Papagelopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.A.","family":"Zahos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.D.","family":"Kolia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.G.","family":"Poulakou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.E.","family":"Falagas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,2,21]]},"reference":[{"key":"e_1_2_4_2_2","first-page":"198","article-title":"Infections with rapidly growing mycobacteria","volume":"7","author":"Sungkanuparph S","year":"2003","journal-title":"report of 20 cases"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1080\/026886901750353737"},{"key":"e_1_2_4_4_2","first-page":"405","article-title":"Skin, soft tissue, and bone infections due to Mycobacterium chelonae chelonae","volume":"166","author":"Wallace RJ","year":"1992","journal-title":"importance of prior corticosteroid therapy, frequency of disseminated infections and resistance to oral antimicrobials other than clarithromycin"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/clind\/16.4.463"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1086\/322523"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/120347540100500107"},{"key":"e_1_2_4_8_2","first-page":"418","article-title":"Vertebral osteomyelitis","volume":"11","author":"Abramovitz JN","year":"1986","journal-title":"the surgical management of neurological complications"},{"key":"e_1_2_4_9_2","first-page":"1890","article-title":"Evaluation of the risk of instrumentation as a foreign body in the spinal tuberculosis","volume":"18","author":"Oga M","year":"1993","journal-title":"clinical and biological study"},{"key":"e_1_2_4_10_2","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.2106\/00004623-199909000-00007","article-title":"Anterior instrumentation for the treatment of spinal tuberculosis","volume":"81","author":"Yilmaz C","year":"1999","journal-title":"J Bone Joint Surg Am"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-003-0661-5"},{"key":"e_1_2_4_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.1.181-182.2000"},{"key":"e_1_2_4_13_2","first-page":"163","article-title":"Emergence of resistance to clarithromycin during treatment of disseminated cutaneous Mycobacterium chelonae infection","volume":"43","author":"Vemulapalli RK","year":"2001","journal-title":"case report and literature review"},{"key":"e_1_2_4_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.46.10.3164-3167.2002"},{"key":"e_1_2_4_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.45.3.764-767.2001"},{"key":"e_1_2_4_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199312000-00032"}],"container-title":["Transplant Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-3062.2006.00178.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-3062.2006.00178.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T09:37:53Z","timestamp":1696930673000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-3062.2006.00178.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,2,21]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["10.1111\/j.1399-3062.2006.00178.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-3062.2006.00178.x","archive":["Portico"],"relation":{},"ISSN":["1398-2273","1399-3062"],"issn-type":[{"value":"1398-2273","type":"print"},{"value":"1399-3062","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,2,21]]}}}