{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:02:45Z","timestamp":1761512565082},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,12,13]],"date-time":"2007-12-13T00:00:00Z","timestamp":1197504000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:p><jats:bold>Abstract: <\/jats:bold> Immune globulin intravenous (human) (IGIV) is effective in the treatment of various autoimmune and inflammatory disorders. Recently, high\u2010dose IGIV 2\u2003g\/kg has been utilized in the treatment of antibody\u2010mediated rejection in solid organ transplantation. We report a renal transplant recipient who developed aseptic meningitis and diplopia from abducens nerve (cranial nerve VI) palsy following IGIV administration for antibody\u2010mediated rejection. Potential mechanisms of the IGIV\u2010related aseptic meningitis are elaborated. Clinicians should be aware of aseptic meningitis and cranial nerve palsy as an adverse reaction to IGIV exposure and monitor for its signs and symptoms.<\/jats:p>","DOI":"10.1111\/j.1399-3062.2007.00294.x","type":"journal-article","created":{"date-parts":[[2008,7,23]],"date-time":"2008-07-23T12:37:21Z","timestamp":1216816641000},"page":"294-297","source":"Crossref","is-referenced-by-count":16,"title":["Aseptic meningitis and abducens nerve palsy as a serious side effect of high dose intravenous immunoglobulin used in a patient with renal transplantation"],"prefix":"10.1111","volume":"10","author":[{"given":"S.E.","family":"Wright","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z.H.A.","family":"Shaikh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.A.","family":"Castillo\u2010Lugo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Tanriover","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,7,23]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"85S","article-title":"The patient","volume":"25","author":"Harvey R.","year":"2005","journal-title":"emerging clinical applications of intravenous immunoglobulin"},{"key":"e_1_2_5_3_2","first-page":"1460","article-title":"Intravenous immune globulins","volume":"43","author":"Knezevic\u2010Maramica I","year":"2003","journal-title":"an update for clinicians"},{"key":"e_1_2_5_4_2","first-page":"653","article-title":"Utility of intravenous immune globulin in kidney transplantation","volume":"3","author":"Jordan S","year":"2003","journal-title":"efficacy, safety and cost implications"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2005.09.128"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199809270-00017"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000029941.34837.22"},{"key":"e_1_2_5_8_2","first-page":"215","article-title":"Drug induced aseptic meningitis","author":"Jolles S","year":"2000","journal-title":"diagnosis and management"},{"key":"e_1_2_5_9_2","first-page":"259","article-title":"Aseptic meningitis associated with high\u2010dose intravenous immunoglobulin therapy","volume":"121","author":"Sekul EA","year":"1994","journal-title":"frequency and risk factors"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-121-4-199408150-00014"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199301073280104"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.54.3.768"},{"key":"e_1_2_5_13_2","first-page":"760","article-title":"Diabetes and hypertension in isolated sixth nerve palsy","volume":"112","author":"Patel SV","year":"2005","journal-title":"a population-based study"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.159.11.1185"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.4065\/74.9.907"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/eye.1995.110"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1981.154"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/00043426-199911000-00012"}],"container-title":["Transplant Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-3062.2007.00294.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-3062.2007.00294.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T17:59:06Z","timestamp":1696874346000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-3062.2007.00294.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7,23]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,8]]}},"alternative-id":["10.1111\/j.1399-3062.2007.00294.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-3062.2007.00294.x","archive":["Portico"],"relation":{},"ISSN":["1398-2273","1399-3062"],"issn-type":[{"value":"1398-2273","type":"print"},{"value":"1399-3062","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,7,23]]}}}