{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T10:48:11Z","timestamp":1788691691564,"version":"build-2803163510"},"reference-count":16,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,8,26]],"date-time":"2011-08-26T00:00:00Z","timestamp":1314316800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2011,10]]},"abstract":"<jats:p>R. Rodr\u00edguez\u2010Romo, L.E. Morales\u2010Buenrostro, L. Lecuona, N. Escalante\u2010Santill\u00e1n, A. Velasco\u2010Villa, I. Kuzmin, C.E. Rupprecht, C. De\u2010Leo, J. Ram\u00edrez, J. Alber\u00fa. Immune response after rabies vaccine in a kidney transplant recipient.\u2028Transpl Infect Dis 2011: <jats:bold>13:<\/jats:bold> 492\u2013495. All rights reserved<\/jats:p><jats:p><jats:bold>Abstract: <\/jats:bold> A 48\u2010year\u2010old male kidney\u2010transplant recipient was bitten by a rabid dog. His immunosuppressive treatment consisted of cyclosporine 60\u2003mg b.i.d., mycophenolate mofetil (MMF) 250\u2003mg t.i.d., and prednisone 5\u2003mg. After wound care, he received 5 doses of purified vero cell rabies vaccine on days 0, 3, 7, 14, and 28, and human rabies immunoglobulin, according to international guidelines. Adequate levels of rabies virus neutralizing antibodies were observed after the administration of the third vaccine dose. However, a decrease of antibody titer was detected by day 28. Immunosuppressive medication was minimized, withdrawing MMF and reducing the dose of cyclosporine. Booster doses of the same vaccine were administered on days 38, 41, 45, 52, and 66. Adequate neutralizing antibody response was recovered during the ensuing 12 months, under reduced immunosuppression. Nineteen months after the incident, the patient remains with good graft function and is asymptomatic for rabies. It remains to be determined whether the attained immune response was either the result of the booster vaccinations or the reduction of immunosuppression alone. Nevertheless, such an outcome would have been possible only with the combined management strategy implemented.<\/jats:p>","DOI":"10.1111\/j.1399-3062.2011.00665.x","type":"journal-article","created":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T03:07:18Z","timestamp":1314846438000},"page":"492-495","source":"Crossref","is-referenced-by-count":16,"title":["Immune response after rabies vaccine in a kidney transplant recipient"],"prefix":"10.1111","volume":"13","author":[{"given":"R.","family":"Rodr\u00edguez\u2010Romo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.E.","family":"Morales\u2010Buenrostro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Lecuona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Escalante\u2010Santill\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Velasco\u2010Villa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Kuzmin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.E.","family":"Rupprecht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"De\u2010Leo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Ram\u00edrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Alber\u00fa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,8,26]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2008.03.010"},{"key":"e_1_2_6_3_2","first-page":"2751","article-title":"Successful protection of humans exposed to rabies infection","volume":"236","author":"Bahmanyar M","year":"1976","journal-title":"post-exposure treatment with the new human diploid cell rabies vaccine and antirabies serum"},{"key":"e_1_2_6_4_2","volume-title":"WHO expert consultation on rabies: first report","author":"World Health Organization","year":"2005"},{"key":"e_1_2_6_5_2","unstructured":"CENAVECE Ministry of Health Mexico. 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