{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:19:27Z","timestamp":1787066367097,"version":"build-2736575974"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,8,26]],"date-time":"2011-08-26T00:00:00Z","timestamp":1314316800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:p>N. Theodoropoulos, F. Lanternier, J. Rassiwala, G. McNatt, L. Preczewski, E. DeMayo, V. Stosor, M.G. Ison. Use of the QuantiFERON\u2010TB Gold interferon\u2010gamma release assay for screening transplant candidates: a single\u2010center retrospective study.\u2028Transpl Infect Dis 2011. All rights reserved<\/jats:p>\n                  <jats:p>\n                    <jats:bold>Background.<\/jats:bold>\n                    Tuberculosis (TB) reactivation is a rare but significant complication of organ transplantation, and screening of all transplant candidates for latent infection is recommended with either an interferon\u2010\u03b3 release assay (IGRA) or tuberculin skin test (TST).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods.<\/jats:bold>\n                    After institutional review board approval, we retrospectively collected data to describe the yield of transplant candidate screening using the QuantiFERON\u2010TB Gold (QFT) and QuantiFERON\u2010TB Gold In\u2010Tube (QFT\u2010IT) assays since the institution of TB screening in 2008 and the epidemiology of all cases of post\u2010transplant TB in our institution since 2004.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results.<\/jats:bold>\n                    A total of 2392 patients were screened with either the QFT or QFT\u2010IT assay through October 2009; 245 (10.2%) tested positive and 206 (8.6%) were indeterminate. Of those with positive results, 107 (43.7%) were foreign born and most of the remainder had prior TB exposures. Of the tests performed at a reference lab, 29% were indeterminate, whereas 14% were indeterminate using our in\u2010house lab. The majority of indeterminate results were seen in liver transplant candidates (40.6% vs. 11.8% in non\u2010liver candidates). Three of 694 (0.43%) screened patients who underwent transplantation developed TB post transplant.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions.<\/jats:bold>\n                    Post\u2010transplant TB occurs at a low rate with universal IGRA\u2010based candidate screening, which is comparable to studies using TST screening.\n                  <\/jats:p>","DOI":"10.1111\/j.1399-3062.2011.00666.x","type":"journal-article","created":{"date-parts":[[2011,8,31]],"date-time":"2011-08-31T23:07:12Z","timestamp":1314832032000},"page":"1-8","source":"Crossref","is-referenced-by-count":44,"title":["Use of the QuantiFERON\u2010TB Gold interferon\u2010gamma release assay for screening transplant candidates: a single\u2010center retrospective study"],"prefix":"10.1111","volume":"14","author":[{"given":"N.","family":"Theodoropoulos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Lanternier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Rassiwala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"McNatt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Preczewski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"DeMayo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Stosor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.G.","family":"Ison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,8,26]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2009.02894.x"},{"issue":"5","key":"e_1_2_7_3_2","first-page":"1266","article-title":"Mycobacterium 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