{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T02:17:05Z","timestamp":1793413025282,"version":"4.5.0"},"reference-count":36,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,9,26]],"date-time":"2011-09-26T00:00:00Z","timestamp":1316995200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:title>Abstract:<\/jats:title><jats:p>Ureteral stent insertion at the time of renal transplantation significantly decreases complications of urine leakage and obstruction, but bears an intrinsic risk of microbial colonization. Associated urinary tract infection (<jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content>) may pose a significant risk for graft infection and subsequent graft failure, in particular, during high\u2010level immunosuppression in the early phase after transplantation. The aims of this prospective study were (i) to assess the frequency of microbial ureteral stent colonization (<jats:styled-content style=\"fixed-case\">MUSC<\/jats:styled-content>) in renal transplant recipients by sonication, (ii) to compare the diagnostic value of sonication with that of conventional urine culture (<jats:styled-content style=\"fixed-case\">CUC<\/jats:styled-content>), (iii) to determine biofilm forming organisms, and (iv) to investigate the influence of<jats:styled-content style=\"fixed-case\">MUSC<\/jats:styled-content>on the short\u2010time functional outcome. A total of 80 ureteral stents from 78 renal transplant recipients (deceased donors<jats:italic>n<\/jats:italic>\u00a0=\u00a050, living donors<jats:italic>n<\/jats:italic>\u00a0=\u00a028) were prospectively included in the study.<jats:styled-content style=\"fixed-case\">CUC<\/jats:styled-content>was obtained prior to renal transplantation and at ureteral stent removal. In addition, a new stent sonication technique was performed to dislodge adherent microorganisms.<jats:styled-content style=\"fixed-case\">CUC<\/jats:styled-content>s were positive in 4% of patients. Sonicate\u2010fluid culture significantly increased the yield of microbial growth to 27% (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001). Most commonly isolated microorganisms by sonication were<jats:italic>Enterococcus<\/jats:italic>species (31%), coagulase\u2010negative staphylococci (19%), and<jats:italic>Lactobacillus<\/jats:italic>species (19%), microorganisms not commonly observed in<jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content>s after renal transplantation. The median glomerular filtraton rate (<jats:styled-content style=\"fixed-case\">GFR<\/jats:styled-content>) of the study population increases from 39 mL\/min immediately after transplantation (time point A) to 50 mL\/min 6\u00a0month post transplantation (time point B). In patients without<jats:styled-content style=\"fixed-case\">MUSC<\/jats:styled-content>, the<jats:styled-content style=\"fixed-case\">GFR<\/jats:styled-content>improves from 39 mL\/min (A) to 48 mL\/min (B) and in patients with<jats:styled-content style=\"fixed-case\">MUSC<\/jats:styled-content>from 39 mL\/min (A) to 50 mL\/min (B), respectively. In summary,<jats:styled-content style=\"fixed-case\">MUSC<\/jats:styled-content>in renal transplant recipients is common and remains frequently undetected by routine<jats:styled-content style=\"fixed-case\">CUC<\/jats:styled-content>, but colonization had no measurable effect on renal function.<\/jats:p>","DOI":"10.1111\/j.1399-3062.2011.00671.x","type":"journal-article","created":{"date-parts":[[2011,9,28]],"date-time":"2011-09-28T00:57:28Z","timestamp":1317171448000},"page":"57-63","source":"Crossref","is-referenced-by-count":32,"title":["Microbial ureteral stent colonization in renal transplant recipients: frequency and influence on the short\u2010time functional outcome"],"prefix":"10.1111","volume":"14","author":[{"given":"G.","family":"Bonkat","sequence":"first","affiliation":[{"name":"Department of Urology University Hospital Basel Basel 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