{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T02:32:31Z","timestamp":1761964351113},"reference-count":17,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,1,20]],"date-time":"2012-01-20T00:00:00Z","timestamp":1327017600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:title>Abstract:<\/jats:title><jats:p>Brucellosis is considered the most widespread zoonosis in the world. It has been reported that the prevalence of seropositivity among the <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>urkish population varies from 3% to 14%. We present a case of brucellosis after pediatric liver transplantation. A 15\u2010year\u2010old boy with the diagnosis of neuro <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>ilson's disease underwent deceased\u2010donor liver transplantation. The postoperative immunosuppressive protocol consisted of steroids and tacrolimus. Two months after the operation the patient experienced fever to 40\u00b0C. The patient complained of poor appetite, headache, and diarrhea. He had had pancytopenia. Despite administration of appropriate antibiotics, antiviral and antifungal agents, fever persisted for &gt;\u00a01\u00a0month. Multiple blood, urine, stool, and sputum cultures were negative. Bone marrow aspirate revealed hypocellularity. Liver biopsy was performed, but rejection was not observed on biopsy specimen. <jats:italic><jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>rucella<\/jats:italic> serology was positive and <jats:italic><jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>rucella<\/jats:italic> agglutination titer was 1:320. Bone marrow culture was positive for <jats:italic><jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>rucella<\/jats:italic> but blood culture was negative. The patient was then treated with oral doxycyline and rifampin for 8\u00a0weeks. No previous case report about <jats:italic><jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>rucella<\/jats:italic> infection after liver transplantation has appeared in the literature, to our knowledge; our case is presented as the first. Bone marrow hypoplasia is a rare feature of <jats:italic><jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>rucella<\/jats:italic> infection. Our patient with brucellosis and pancytopenia had had hypocellular bone marrow. The clinical and hematologic findings resolved with treatment of the infection. <jats:italic><jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>rucella<\/jats:italic> infection should be suspected in liver transplanted recipients with fever of unknown origin, especially in a recipient who has lived in an endemic area. <jats:italic><jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>rucella<\/jats:italic> also should be considered as a possible diagnosis in patients with pancytopenia.<\/jats:p>","DOI":"10.1111\/j.1399-3062.2011.00709.x","type":"journal-article","created":{"date-parts":[[2012,1,20]],"date-time":"2012-01-20T05:34:42Z","timestamp":1327037682000},"page":"326-329","source":"Crossref","is-referenced-by-count":15,"title":["<i><scp>B<\/scp>rucella<\/i> infection with pancytopenia after pediatric liver transplantation"],"prefix":"10.1111","volume":"14","author":[{"given":"K.Y.","family":"Polat","sequence":"first","affiliation":[{"name":"Department of Transplant Surgery Memorial Atasehir Hospital Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.S.","family":"Tosun","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology Hepatology and Nutrition Faculty of Medicine Ataturk University Erzurum Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Ertekin","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology Hepatology and Nutrition Istanbul Faculty of Medicine Istanbul University Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Aydinli","sequence":"additional","affiliation":[{"name":"Department of Transplant Surgery Faculty of Medicine Ataturk University Erzurum Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Emre","sequence":"additional","affiliation":[{"name":"Department of Transplant Surgery and Immunology Yale 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