{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:11:27Z","timestamp":1791223887404,"version":"4.1.0"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,3,11]],"date-time":"2005-03-11T00:00:00Z","timestamp":1110499200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bipolar Disorders"],"published-print":{"date-parts":[[2005,4]]},"abstract":"<jats:p><jats:bold>Objectives:\u2002<\/jats:bold> To compare the quality of life (QOL) of patients having dual diagnosis of bipolar affective disorder and substance dependence with those having either diagnosis alone and with healthy controls.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Cross\u2010sectional assessment of the four groups of subjects was made. Euthymic bipolar patients and those substance dependent patients not in active withdrawal or intoxication were included. QOL assessment was made with the World Health Organization (WHO)\u2010QOL \u2013 Bref Hindi version.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Total QOL score and scores on all the four domains of WHO\u2010QOL\u2010Bref were significantly lower for the dual\u2010diagnosis (DD) patients when compared with all the other groups. Significant negative correlations were found between (i) the number of days the drug was consumed and the score on the \u2018general well\u2010being\u2019 items of WHO\u2010QOL\u2010Bref (<jats:italic>r<\/jats:italic>\u2003=\u2003\u22120.31, p\u2003&lt;\u20030.05); and (ii) between severity of alcohol dependence and WHO\u2010QOL total score (<jats:italic>r<\/jats:italic>\u2003=\u2003\u22120.44, p\u2003&lt;\u20030.01) as well as its \u2018psychological\u2019 domain (<jats:italic>r<\/jats:italic>\u2003=\u2003\u22120.52, p\u2003&lt;\u20030.05).<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> The study indicates that bipolar DD patients experience a lower QOL when compared with the other groups studied. Their QOL is affected by the severity of alcohol dependence.<\/jats:p>","DOI":"10.1111\/j.1399-5618.2004.00173.x","type":"journal-article","created":{"date-parts":[[2005,3,11]],"date-time":"2005-03-11T11:52:11Z","timestamp":1110541931000},"page":"187-191","source":"Crossref","is-referenced-by-count":72,"title":["Quality of life and its correlates in patients with dual diagnosis of bipolar affective disorder and substance dependence"],"prefix":"10.1111","volume":"7","author":[{"given":"Jaspreet","family":"Singh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Surendra K","family":"Mattoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pratap","family":"Sharan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debasish","family":"Basu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,3,11]]},"reference":[{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-0327(96)00016-X"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(99)00042-7"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3956(97)00030-7"},{"issue":"1","key":"e_1_2_11_5_2","first-page":"19","article-title":"Psychiatric comorbidity in bipolar disorder","volume":"5","author":"Tondo L","year":"2003","journal-title":"Bipolar Disord"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v60n1103"},{"key":"e_1_2_11_7_2","first-page":"490","article-title":"Would manic rather land? Function and quality of life in patients with bipolar disorder","volume":"18","author":"Vojta CL","year":"1998","journal-title":"Med Decis Making"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1989.tb01336.x"},{"key":"e_1_2_11_9_2","volume-title":"The ICD\u201010 Classification of Mental and Behavioural Disorders: Clinical Descriptions and Diagnostic Guidelines","author":"World Health Organization","year":"1992"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.2044-8341.1959.tb00467.x"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1979.tb04484.x"},{"key":"e_1_2_11_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360-0443.1983.tb05502.x"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4603(82)90005-3"},{"key":"e_1_2_11_14_2","first-page":"160","article-title":"WHO\u2010QOL Hindi: a questionnaire for assessing quality of life in health care setting in India","volume":"11","author":"Saxena S","year":"1988","journal-title":"Nat Med J India"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291798006667"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.3109\/00952999809019617"},{"key":"e_1_2_11_17_2","doi-asserted-by":"publisher","DOI":"10.15288\/jsa.1999.60.653"}],"container-title":["Bipolar Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-5618.2004.00173.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-5618.2004.00173.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T15:50:21Z","timestamp":1696866621000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-5618.2004.00173.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,3,11]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,4]]}},"alternative-id":["10.1111\/j.1399-5618.2004.00173.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-5618.2004.00173.x","archive":["Portico"],"relation":{},"ISSN":["1398-5647","1399-5618"],"issn-type":[{"value":"1398-5647","type":"print"},{"value":"1399-5618","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,3,11]]}}}