{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T04:17:28Z","timestamp":1789532248414,"version":"build-2803163510"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,1,21]],"date-time":"2005-01-21T00:00:00Z","timestamp":1106265600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2005,2]]},"abstract":"<jats:p><jats:bold>Background:\u2002<\/jats:bold> Today, patients with chronic respiratory failure are commonly treated with non\u2010invasive bi\u2010level positive airway pressure ventilation, supporting spontaneous breathing. However, in conformity with previous clinical routine, many post\u2010polio patients with chronic respiratory failure are still treated with invasive (i.e. via a tracheostomy) controlled mechanical ventilation (CMV). The aim of the study was to investigate the effect of invasive bi\u2010level positive airway pressure ventilation on the work of breathing compared with that during the patients' ordinary CMV and spontaneous breathing without mechanical support.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Nine post\u2010polio patients on invasive (tracheostomy) nocturnal CMV were investigated. Work of breathing was analysed by assessing differences in oxygen consumption (VO<jats:sub>2<\/jats:sub>) using indirect calorimetry. Hereby, the oxygen cost of breathing during the various ventilatory modes could be estimated and related to one another. Data on energy expenditure were also obtained.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> The oxygen cost of breathing decreased by approximately 15% during bi\u2010level positive airway pressure ventilation compared with CMV and spontaneous breathing. There was no difference between predicted (Harris\u2013Benedict equation) and measured energy expenditure.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> Invasive bi\u2010level positive airway pressure ventilation reduces the oxygen cost of breathing in long\u2010standing tracheostomized post\u2010polio patients, compared with CMV. Furthermore, the Harris\u2013Benedict equation provides a reasonable prediction of energy expenditure in this group of patients.<\/jats:p>","DOI":"10.1111\/j.1399-6576.2004.00566.x","type":"journal-article","created":{"date-parts":[[2005,2,16]],"date-time":"2005-02-16T23:09:54Z","timestamp":1108595394000},"page":"197-202","source":"Crossref","is-referenced-by-count":12,"title":["Bi\u2010level positive airway pressure ventilation reduces the oxygen cost of breathing in long\u2010standing post\u2010polio patients on invasive home mechanical ventilation"],"prefix":"10.1111","volume":"49","author":[{"given":"H.","family":"Barle","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"S\u00f6derberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Haegerstrand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Markstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,2,16]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.55.1.4"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.4.412"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.122.5.1695"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.03.00029803"},{"key":"e_1_2_6_6_2","first-page":"161","article-title":"A historical perspective on the use of noninvasive ventilatory support alternatives","volume":"2","author":"Bach JR","year":"1996","journal-title":"Respir Care Clin N Am"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1078-5337(02)00040-0"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1995.tb27535.x"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.55.5.417"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.57.3.192"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00075198-200304000-00005"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.97.10010184"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198802000-00004"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.93.3.506"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01726538"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01701474"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199809000-00018"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1177\/0148607197021003168"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001340100941"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1177\/014860710302700116"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1054\/clnu.2001.0473"},{"key":"e_1_2_6_22_2","volume-title":"A Biometric Study of Basal Metabolism in Man.","author":"Harris J","year":"1919"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01711217"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199111000-00017"},{"key":"e_1_2_6_25_2","volume-title":"Handbook of Gas Exchange and Indirect Calorimetry 1991.","author":"Takala J"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1164\/arrd.1986.134.5.902"},{"key":"e_1_2_6_27_2","first-page":"11","volume-title":"Nutrition and Metabolism in Chronic Respiratory Disease.","author":"Hugli O","year":"2003"}],"container-title":["Acta Anaesthesiologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-6576.2004.00566.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-6576.2004.00566.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T16:41:25Z","timestamp":1696869685000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-6576.2004.00566.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,2]]}},"alternative-id":["10.1111\/j.1399-6576.2004.00566.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-6576.2004.00566.x","archive":["Portico"],"relation":{},"ISSN":["0001-5172","1399-6576"],"issn-type":[{"value":"0001-5172","type":"print"},{"value":"1399-6576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,2]]}}}