{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T20:56:13Z","timestamp":1761512173334},"reference-count":16,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2005,10,13]],"date-time":"2005-10-13T00:00:00Z","timestamp":1129161600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2005,11]]},"abstract":"<jats:p>We report a clinical and neuroradiological description of a severe case of Wernicke's encephalopathy in a surgical patient. After colonic surgery for neoplasm, he was treated for a long time with high glucose concentration total parenteral nutrition. In the early post\u2010operative period, the patient showed severe encephalopathy with ataxia, ophthalmoplegia and consciousness disorders. We used magnetic resonance imaging (MRI) to confirm the clinical suspicion of Wernicke's encephalopathy. The radiological feature showed hyperintense lesions which were symmetrically distributed along the bulbo\u2010pontine tegmentum, the tectum of the mid\u2010brain, the periacqueductal grey substance, the hypothalamus and the medial periventricular parts of the thalamus. This progressed to typical Wernicke\u2013Korsakoff syndrome with ataxia and memory and cognitive defects. Thiamine deficiency is a re\u2010emerging problem in non\u2010alcoholic patients and it may develop in surgical patients with risk factors such as malnutrition, prolonged vomiting and long\u2010term high glucose concentration parenteral nutrition.<\/jats:p>","DOI":"10.1111\/j.1399-6576.2005.00879.x","type":"journal-article","created":{"date-parts":[[2005,11,15]],"date-time":"2005-11-15T15:18:40Z","timestamp":1132067920000},"page":"1566-1570","source":"Crossref","is-referenced-by-count":28,"title":["Wernicke's encephalopathy in a malnourished surgical patient: clinical features and magnetic resonance imaging"],"prefix":"10.1111","volume":"49","author":[{"given":"M.","family":"Nolli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Barbieri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Pinna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Pasetto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Nicosia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,10,13]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0248-8663(00)00248-4"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/0148607185009002216"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/0148607191015002200"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)93117-6"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.55.9.826"},{"key":"e_1_2_5_7_2","first-page":"2555","article-title":"Thiamine status in patients receiving long\u2010term home parenteral nutrition","volume":"91","author":"Schiano TD","year":"1996","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_5_8_2","first-page":"171","article-title":"Acute encephalopathy due to thiamine deficiency (Wernicke's encephalopathy) in a chronic hemodialyzed patient: a case report","volume":"35","author":"Descombes E","year":"1991","journal-title":"Clin Nephrol"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410210114"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.58.683.558"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1159\/000117034"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.57.9.1356"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.57.3.405"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.171.4.9763009"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6569.2001.tb00070.x"},{"key":"e_1_2_5_16_2","first-page":"1480","article-title":"Wernicke's Encephalopathy: Atypical Manifestation at MR Imaging","volume":"22","author":"Bae SJ","year":"2001","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-199503000-00026"}],"container-title":["Acta Anaesthesiologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-6576.2005.00879.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-6576.2005.00879.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T01:04:44Z","timestamp":1697418284000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-6576.2005.00879.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,10,13]]},"references-count":16,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2005,11]]}},"alternative-id":["10.1111\/j.1399-6576.2005.00879.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-6576.2005.00879.x","archive":["Portico"],"relation":{},"ISSN":["0001-5172","1399-6576"],"issn-type":[{"value":"0001-5172","type":"print"},{"value":"1399-6576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,10,13]]}}}