{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T04:17:29Z","timestamp":1789532249282,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,4,25]],"date-time":"2006-04-25T00:00:00Z","timestamp":1145923200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2006,5]]},"abstract":"<jats:p><jats:bold>Background:\u2002<\/jats:bold> Patients suffering from post\u2010polio syndrome still contribute significantly to the number of patients with chronic respiratory failure requiring home mechanical ventilation (HMV). Many of these patients are treated either with invasive (tracheostomy) or non\u2010invasive (nasal mask) controlled mechanical ventilation i.e. volume\u2010controlled ventilation (VCV). In this group of patients, we have previously shown that bi\u2010level pressure support ventilation (bi\u2010level PSV) decreases the oxygen cost of breathing. The aim of this study was to compare the effect of bi\u2010level PSV, with special regard to the adequacy of ventilation and the oxygen cost of breathing, during the patients' ordinary VCV and spontaneous breathing.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Eight post\u2010polio patients on nocturnal VCV were investigated. Five of them were tracheostomized and three of them used a nasal mask. Work of breathing was analysed by assessing differences in oxygen consumption (VO<jats:sub>2<\/jats:sub>) using indirect calorimetry. Blood gases were obtained regularly to assess adequacy of ventilation.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Bi\u2010level PSV decreases the oxygen cost of breathing in post\u2010polio patients with respiratory failure without decreasing ventilation efficiency. Furthermore, PaCO<jats:sub>2<\/jats:sub> decreased significantly using this mode of ventilation (<jats:italic>P\u2003&lt;<\/jats:italic>\u20030.05).<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> In this study, it was shown that bi\u2010level PSV reduces the oxygen cost of breathing and gave a significant decrease in PaCO<jats:sub>2<\/jats:sub> in PPS patients. These data suggest that bi\u2010level PSV ventilation maintains adequate ventilation in patients who suffer from post\u2010polio syndrome with respiratory failure.<\/jats:p>","DOI":"10.1111\/j.1399-6576.2006.001015.x","type":"journal-article","created":{"date-parts":[[2006,4,25]],"date-time":"2006-04-25T13:15:17Z","timestamp":1145970917000},"page":"580-585","source":"Crossref","is-referenced-by-count":11,"title":["Bi\u2010level positive airway pressure ventilation maintains adequate ventilation in post\u2010polio patients with respiratory failure"],"prefix":"10.1111","volume":"50","author":[{"given":"C.","family":"Gillis\u2010Haegerstrand","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Markstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Barle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,4,25]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.healthpol.2004.06.001"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20259"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.97.10010146"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1078-5337(02)00040-0"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.55.1.4"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.4.412"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.122.5.1695"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.02.00211902"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1053\/rmed.1999.0699"},{"key":"e_1_2_6_11_2","first-page":"161","article-title":"A historical perspective on the use of noninvasive ventilatory support alternatives","volume":"2","author":"Bach JR","year":"1996","journal-title":"Respir Care Clin N Am"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00066704"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1053\/rmed.1999.0699"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2004.00566.x"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198802000-00004"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.1988.tb02810.x"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01711217"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01726538"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01701474"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199809000-00018"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1177\/0148607197021003168"},{"key":"e_1_2_6_22_2","volume-title":"A Biometric Study of Basal Metabolism in Man.","author":"Harris J","year":"1919"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.101.2.516"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.122.6.2105"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.89.5.677"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198910000-00015"}],"container-title":["Acta Anaesthesiologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-6576.2006.001015.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-6576.2006.001015.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T04:30:58Z","timestamp":1696912258000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-6576.2006.001015.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,4,25]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2006,5]]}},"alternative-id":["10.1111\/j.1399-6576.2006.001015.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-6576.2006.001015.x","archive":["Portico"],"relation":{},"ISSN":["0001-5172","1399-6576"],"issn-type":[{"value":"0001-5172","type":"print"},{"value":"1399-6576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,4,25]]}}}