{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T15:23:43Z","timestamp":1790609023168,"version":"4.1.0"},"reference-count":71,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2007,1,11]],"date-time":"2007-01-11T00:00:00Z","timestamp":1168473600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2007,3]]},"abstract":"<jats:p><jats:bold>Background:\u2002<\/jats:bold> In order to avoid peri\u2010operative hypovolaemia or fluid overload, goal\u2010directed therapy with individual maximization of flow\u2010related haemodynamic parameters has been introduced. The objectives of this review are to update research in the area, evaluate the effects on outcome and assess the use of strategies, parameters and monitors for goal\u2010directed therapy.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> A MEDLINE search (1966 to 2 October 2006) was performed to identify studies in which a goal\u2010directed therapeutic strategy was used to maximize flow\u2010related haemodynamic parameters in surgical patients, as well as studies referenced from these papers. Furthermore, methods applied in these studies and other monitors with a potential for goal\u2010directed therapy are described.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Nine studies were identified pertaining to fluid optimization during the intra\u2010 and post\u2010operative period with goal\u2010directed therapy. Seven studies (<jats:italic>n<\/jats:italic>= 725) found a reduced hospital stay. Post\u2010operative nausea and vomiting (PONV) and ileus were reduced in three studies and complications were reduced in four studies. Of the monitors that may be applied for goal\u2010directed therapy, only oesophageal Doppler has been tested adequately; however, several other options exist.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> Goal\u2010directed therapy with the maximization of flow\u2010related haemodynamic variables reduces hospital stay, PONV and complications, and facilitates faster gastrointestinal functional recovery. So far, oesophageal Doppler is recommended, but other monitors are available and call for evaluation.<\/jats:p>","DOI":"10.1111\/j.1399-6576.2006.01221.x","type":"journal-article","created":{"date-parts":[[2007,1,11]],"date-time":"2007-01-11T09:41:43Z","timestamp":1168508503000},"page":"331-340","source":"Crossref","is-referenced-by-count":214,"title":["Monitoring of peri\u2010operative fluid administration by individualized goal\u2010directed therapy"],"prefix":"10.1111","volume":"51","author":[{"given":"M.","family":"Bundgaard\u2010Nielsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Holte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. 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