{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T18:13:38Z","timestamp":1793643218970,"version":"4.5.1"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2007,11,15]],"date-time":"2007-11-15T00:00:00Z","timestamp":1195084800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2008,2]]},"abstract":"<jats:p>\n                    <jats:bold>Objective:<\/jats:bold>\n                    To assess lung volume changes during and after bronchoscopic suctioning during volume or pressure\u2010controlled ventilation (VCV or PCV).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Design:<\/jats:bold>\n                    Bench test and patient study.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Participants:<\/jats:bold>\n                    Ventilator\u2010treated acute lung injury (ALI) patients.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Setting:<\/jats:bold>\n                    University research laboratory and general adult intensive care unit of a university hospital.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Interventions:<\/jats:bold>\n                    Bronchoscopic suctioning with a 12 or 16\u2003Fr bronchoscope during VCV or PCV.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Measurements and results:<\/jats:bold>\n                    Suction flow at vacuum levels of \u221220 to \u221280\u2003kPa was measured with a Timeter\n                    <jats:sup>\u2122<\/jats:sup>\n                    instrument. In a water\u2010filled lung model, airway pressure, functional residual capacity (FRC) and tidal volume were measured during bronchoscopic suctioning. In 13 ICU patients, a 16\u2003Fr bronchoscope was inserted into the left or the right main bronchus during VCV or PCV and suctioning was performed. Ventilation was monitored with electric impedance tomography (EIT) and FRC with a modified N\n                    <jats:sub>2<\/jats:sub>\n                    washout\/in technique. Airway pressure was measured via a pressure line in the endotracheal tube. Suction flow through the 16\u2003Fr bronchoscope was 5\u2003l\/min at a vacuum level of \u221220\u2003kPa and 17\u2003l\/min at \u221280\u2003kPa. Derecruitment was pronounced during suctioning and FRC decreased with \u2212479\u00b1472\u2003ml,\n                    <jats:italic>P<\/jats:italic>\n                    &lt;0.001.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    Suction flow through the bronchoscope at the vacuum levels commonly used is well above minute ventilation in most ALI patients. The ventilator was unable to deliver enough volume in either VCV or PCV to maintain FRC and tracheal pressure decreased below atmospheric pressure.\n                  <\/jats:p>","DOI":"10.1111\/j.1399-6576.2007.01499.x","type":"journal-article","created":{"date-parts":[[2009,9,10]],"date-time":"2009-09-10T06:33:18Z","timestamp":1252564398000},"page":"209-218","source":"Crossref","is-referenced-by-count":34,"title":["Bronchoscopic suctioning may cause lung collapse: a lung model and clinical evaluation"],"prefix":"10.1111","volume":"52","author":[{"given":"S.","family":"LINDGREN","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"ODENSTEDT","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"ERLANDSSON","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"GRIVANS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"LUNDIN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"STENQVIST","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,11,15]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.68.1.125"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.86.2.184"},{"key":"e_1_2_5_4_2","first-page":"413","article-title":"[Does directed bronchoscopic bronchial cleansing have an advantage over conventional suctioning? 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