{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T17:27:28Z","timestamp":1748280448428},"reference-count":23,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2011,9,27]],"date-time":"2011-09-27T00:00:00Z","timestamp":1317081600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2011,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Addiction is a feared complication of long\u2010term opioid therapy for chronic pain patients. A screening tool to assess the potential risk of addiction may be helpful.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>ain <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>edication <jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content>uestionnaire (<jats:styled-content style=\"fixed-case\">PMQ<\/jats:styled-content>) was translated into <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>anish by a \u2018forward\u2019 and \u2018backward\u2019 translation procedure. Patients with chronic non\u2010cancer pain and cancer pain treated at a tertiary pain center were screened for addiction using <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>ortenoy's criteria and invited to answer the <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>anish version of the <jats:styled-content style=\"fixed-case\">PMQ<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two hundred nine patients participated in the study. <jats:styled-content style=\"fixed-case\">PMQ<\/jats:styled-content> was able to discriminate between addicted and non\u2010addicted patients. Patients with high <jats:styled-content style=\"fixed-case\">PMQ<\/jats:styled-content> scores indicating a risk of addiction drank more alcohol, smoked more tobacco, used higher doses of morphine, had a higher anxiety and depression score, and had poorer mental health. Using a cut\u2010off score of 22, the <jats:styled-content style=\"fixed-case\">PMQ<\/jats:styled-content> had a sensitivity of 82%, but the specificity at this cut\u2010point was 56%, indicating a risk of false positive cases. Convergent and discriminant validity were confirmed by correlation with opioid doses, alcohol and tobacco use, anxiety and depression scores, and inverse correlation with mental health and social role. Test\u2013retest showed a very strong correlation. Cronbach's alpha for internal consistency was 0.61. Ten components were found to have eigenvalues above 1.0, confirming the multidimensional structure of the questionnaire.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">PMQ<\/jats:styled-content> may assist physicians in addiction risk assessment and stratification when treating chronic pain patients with opioids. <jats:styled-content style=\"fixed-case\">PMQ<\/jats:styled-content> is not a diagnostic tool and should only be used as an indicator for possible addiction problems.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1399-6576.2011.02523.x","type":"journal-article","created":{"date-parts":[[2011,9,28]],"date-time":"2011-09-28T02:29:54Z","timestamp":1317176994000},"page":"1231-1238","source":"Crossref","is-referenced-by-count":9,"title":["Validation and usefulness of the <scp>D<\/scp>anish version of the <scp>P<\/scp>ain <scp>M<\/scp>edication <scp>Q<\/scp>uestionnaire in opioid\u2010treated chronic pain patients"],"prefix":"10.1111","volume":"55","author":[{"given":"J.","family":"H\u00d8JSTED","sequence":"first","affiliation":[{"name":"Multidisciplinary Pain Centre  Rigshospitalet Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. R.","family":"NIELSEN","sequence":"additional","affiliation":[{"name":"Multidisciplinary Pain Centre  Rigshospitalet Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"KENDALL","sequence":"additional","affiliation":[{"name":"Multidisciplinary Pain Centre  Rigshospitalet Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"FRICH","sequence":"additional","affiliation":[{"name":"Multidisciplinary Pain Centre  Rigshospitalet Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"SJ\u00d8GREN","sequence":"additional","affiliation":[{"name":"Section of Acute Pain Management and Palliative Medicine  Rigshospitalet Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,9,27]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2006.08.004"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.18553\/jmcp.2009.15.7.556"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2008.10.008"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/10550490802544508"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2010.04.006"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2003.10.009"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1533-2500.2006.00067.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.5055\/jom.2007.0013"},{"key":"e_1_2_7_10_1","volume-title":"EORTC Quality of Life Group translation procedure","author":"Cull A","year":"2002"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.1997.tb04632.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(97)00059-6"},{"key":"e_1_2_7_13_1","first-page":"331","volume-title":"Oxford textbook of palliative medicine","author":"Hanks G","year":"1998"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.324.7337.606"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002508-200311000-00002"},{"key":"e_1_2_7_16_1","volume-title":"Handbook of research and evaluation","author":"Isaac S","year":"1995"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1533-2500.2009.00316.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002508-199706000-00009"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6963-6-46"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2007.02.014"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2004.04.007"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0b013e3180330dc5"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0b013e31802b4f95"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-010-0118-6"}],"container-title":["Acta Anaesthesiologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-6576.2011.02523.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-6576.2011.02523.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T19:15:51Z","timestamp":1695496551000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-6576.2011.02523.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9,27]]},"references-count":23,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["10.1111\/j.1399-6576.2011.02523.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-6576.2011.02523.x","archive":["Portico"],"relation":{},"ISSN":["0001-5172","1399-6576"],"issn-type":[{"value":"0001-5172","type":"print"},{"value":"1399-6576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,9,27]]}}}