{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T22:33:58Z","timestamp":1784846038313,"version":"3.55.0"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,12,12]],"date-time":"2011-12-12T00:00:00Z","timestamp":1323648000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The purpose of this study was to investigate whether an initial post\u2010operative lactate level is a predictor of mortality, need for peritoneal dialysis (<jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>), duration of intubation or length of stay (<jats:styled-content style=\"fixed-case\">LOS<\/jats:styled-content>) in the intensive care unit (<jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content>) in children undergoing cardiac surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A retrospective, observational follow\u2010up study was conducted in 206 children undergoing cardiac surgery from 2006 to 2007. Multivariate logistics regression analyses were performed to determine whether the lactate level was an independent risk factor. The lactate concentration at arrival in the <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content>, outcome and risk factors (patient demographics, surgical complexity, duration of cardiopulmonary bypass and inotropic score) were obtained from the electronic patient data management program and medical records.<\/jats:p><\/jats:sec><jats:sec><jats:title>Result<\/jats:title><jats:p>The median (interquartile range) lactate level was 1.9\u2009mmol\/l (1.3\u20132.7) in children immediately after cardiac surgery and a mortality of 3.9%. Eight percent of the children had a lactate level higher than 4.5\u2009mmol\/l. An increased lactate level \u22654.5\u2009mmol\/l resulted in an odds ratio (95% confidence intervals) of 8.4 (1.5\u201346.1) for mortality and an odds ratio of 16.9 (2.7\u2013106.8) for PD after adjusting for <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>isk <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>djustment for <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ongenital <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>eart <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>urgery 1. Because of the low number of deaths, limited confounder analysis was performed. Duration of intubation and <jats:styled-content style=\"fixed-case\">LOS<\/jats:styled-content> in the <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content> were not associated with the initial lactate level when adjusting for confounders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The initial post\u2010operative lactate level was a predictor of mortality and need for <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> in children undergoing surgery for congenital heart disease.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1399-6576.2011.02588.x","type":"journal-article","created":{"date-parts":[[2011,12,12]],"date-time":"2011-12-12T18:11:23Z","timestamp":1323713483000},"page":"459-464","source":"Crossref","is-referenced-by-count":20,"title":["Lactate levels predict mortality and need for peritoneal dialysis in children undergoing congenital heart surgery"],"prefix":"10.1111","volume":"56","author":[{"given":"L.","family":"MAARSLET","sequence":"first","affiliation":[{"name":"Department of Anaesthesia and Intensive Care Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. B.","family":"M\u00d8LLER","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"DALL","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"HJORTHOLM","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"RAVN","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,12,12]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2008.10.017"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2005.09.008"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2004.10.010"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)90001-1"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01709563"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.77.3.235"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(97)00527-4"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2005.04.029"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.PCC.0000163979.33774.89"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-007-0593-3"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(97)70018-7"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1067\/mtc.2002.119064"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-007-0987-2"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e31816c6f31"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-010-9724-7"}],"container-title":["Acta Anaesthesiologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-6576.2011.02588.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-6576.2011.02588.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T00:43:04Z","timestamp":1698712984000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-6576.2011.02588.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12,12]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["10.1111\/j.1399-6576.2011.02588.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-6576.2011.02588.x","archive":["Portico"],"relation":{},"ISSN":["0001-5172","1399-6576"],"issn-type":[{"value":"0001-5172","type":"print"},{"value":"1399-6576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,12,12]]}}}