{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T16:02:19Z","timestamp":1770220939058,"version":"3.49.0"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,9,4]],"date-time":"2012-09-04T00:00:00Z","timestamp":1346716800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Throughout the world, drug administration error remains a known and significant threat to patients undergoing anaesthesia. Estimates of the extent of the problem vary, but few are based on large prospectively collected datasets. Furthermore, little is known about whether differences in work culture are important in error rates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective incident monitoring study was conducted at a large tertiary hospital in <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hina to estimate the frequency of drug administration error during anaesthesia. Anaesthetists were asked to return a study form anonymously for every anaesthetic, indicating whether or not a drug administration error had occurred, including incident details if affirmative.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From 24,380 anaesthetics, 16,496 study forms were returned (67.7% response rate), reporting 179 errors. The frequency (95% confidence interval) of drug administration error was 0.73% (0.63% to 0.85%) based on total study anaesthetics and 1.09% (0.93% to 1.26%) based on total forms returned. The largest categories of error were omissions (27%), incorrect doses (23%) and substitutions (20%). Errors resulted in prolonged stay in recovery for 21 patients, transfer to the <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content> for five and one case each of haemorrhagic shock and asthmatic attack. More respondents who were not fully rested reported inattention as a contributing factor to error (21%) than those who were fully rested (7%, <jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content><\/jats:italic>\u2009=\u20090.04).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our results are comparable with other international prospective estimates indicating that drug administration error is of concern in <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hina as elsewhere. These results will form a baseline from which to detect the effects of countermeasures.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1399-6576.2012.02762.x","type":"journal-article","created":{"date-parts":[[2012,9,4]],"date-time":"2012-09-04T15:29:42Z","timestamp":1346772582000},"page":"158-164","source":"Crossref","is-referenced-by-count":58,"title":["The frequency and nature of drug administration error during anaesthesia in a <scp>C<\/scp>hinese hospital"],"prefix":"10.1111","volume":"57","author":[{"given":"Y.","family":"ZHANG","sequence":"first","affiliation":[{"name":"Department of Medical Administration Shengjing Hospital China Medical University  Shenyang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y. J.","family":"DONG","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Shengjing Hospital China Medical University  Shenyang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. S.","family":"WEBSTER","sequence":"additional","affiliation":[{"name":"Centre for Medical and Health Sciences Education Faculty of Medical and Health Sciences University of Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"X. D.","family":"DING","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Shengjing Hospital China Medical University  Shenyang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"X. Y.","family":"LIU","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Shengjing Hospital China Medical University  Shenyang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. M.","family":"CHEN","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Shengjing Hospital China Medical University  Shenyang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. X.","family":"MENG","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Shengjing Hospital China Medical University  Shenyang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"X. Y.","family":"WU","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Shengjing Hospital China Medical University  Shenyang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. N.","family":"WANG","sequence":"additional","affiliation":[{"name":"Institute Office Shengjing Hospital China Medical University  Shenyang China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,9,4]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"To err is human \u2013 building a safer health system","author":"Institute of Medicine","year":"2000"},{"key":"e_1_2_7_3_1","volume-title":"An organisation with a memory \u2013 report of an expert group on learning from adverse events in the NHS","author":"Department of Health","year":"2000"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.anes.0000290620.54964.96"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.2009.06107.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-197812000-00004"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03006159"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1981.tb08650.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1988.tb05606.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1990.tb14492.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1993.tb06781.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03027956"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/0310057X0102900508"},{"key":"e_1_2_7_14_1","first-page":"A1358","article-title":"Anesthesia drug administration error in a university hospital","volume":"99","author":"Bowdle A","year":"2003","journal-title":"Anesthesiology"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/0310057X0903700105"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00540-008-0624-4"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.2010.06325.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2710.2008.00997.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annfar.2011.11.011"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.2005.04123.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d5543"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.3410\/M1\u201069"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2006.01098.x"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-6576.1999.430604.x"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2012.02707.x"}],"container-title":["Acta Anaesthesiologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-6576.2012.02762.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-6576.2012.02762.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T03:28:27Z","timestamp":1700623707000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-6576.2012.02762.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,4]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["10.1111\/j.1399-6576.2012.02762.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-6576.2012.02762.x","archive":["Portico"],"relation":{},"ISSN":["0001-5172","1399-6576"],"issn-type":[{"value":"0001-5172","type":"print"},{"value":"1399-6576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9,4]]}}}