{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T18:23:54Z","timestamp":1776450234767,"version":"3.51.2"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,10,17]],"date-time":"2012-10-17T00:00:00Z","timestamp":1350432000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The rapid and short\u2010acting local anaesthetic articaine is a feasible spinal anaesthetic for day\u2010case open inguinal herniorrhaphy (<jats:styled-content style=\"fixed-case\">OIH<\/jats:styled-content>). We hypothesised that similarly to other spinal local anaesthetics, the addition of fentanyl may prolong articaine spinal analgesia without prolonging motor block.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a randomised, controlled study in 100 adult patients undergoing <jats:styled-content style=\"fixed-case\">OIH<\/jats:styled-content>. Spinal anaesthesia was induced by injecting hyperbaric articaine 72\u2009mg with (<jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>roup <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>\u2009+\u2009<jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>) or without (<jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>roup <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>) fentanyl 10\u2009\u03bcg with the patient in lateral decubitus position. The distribution of sensory block was tested using pinprick and controlled by tilting the operating table 10 up or down. Motor block testing was based on the patient's ability to flex knees and ankles. Rescue analgesic was intravenous (<jats:styled-content style=\"fixed-case\">i.v.<\/jats:styled-content>) fentanyl. Pain scores were registered, and <jats:styled-content style=\"fixed-case\">i.v.<\/jats:styled-content> paracetamol 1\u2009g was given as the first post\u2010operative analgesic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were no differences (<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>\u2009+\u2009<jats:styled-content style=\"fixed-case\">F<\/jats:styled-content> vs. A) in the maximum median extension of the sensory block (<jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>5 vs. <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>5), mean duration of sensory block \u2265\u2009<jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>10 (76\u2009min vs. 73\u2009min), or total duration of sensory (146\u2009min vs. 146\u2009min) or motor block (99\u2009min vs. 107\u2009min). Fewer patients in <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>roup <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>\u2009+\u2009<jats:styled-content style=\"fixed-case\">F<\/jats:styled-content> needed fentanyl (5 vs. 14, <jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content><\/jats:italic>\u2009&lt;\u20090.05) perioperatively or paracetamol (3 vs. 18, <jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content><\/jats:italic>\u2009&lt;\u20090.001) post\u2010operatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Fentanyl 10\u2009\u03bcg added to spinal hyperbaric articaine improved analgesia and reduced analgesic consumption during and after <jats:styled-content style=\"fixed-case\">OIH<\/jats:styled-content>. Fentanyl did not prolong motor block or delay recovery.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1399-6576.2012.02794.x","type":"journal-article","created":{"date-parts":[[2012,10,17]],"date-time":"2012-10-17T13:56:51Z","timestamp":1350482211000},"page":"118-125","source":"Crossref","is-referenced-by-count":11,"title":["Hyperbaric articaine with or without fentanyl in spinal anaesthesia: patient and observer blinded comparison"],"prefix":"10.1111","volume":"57","author":[{"given":"P.","family":"KAIRALUOMA","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Helsinki University Hospital  Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"BACHMANN","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Helsinki University Hospital  Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"KALLIO","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Helsinki University Hospital  Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"ROSENBERG","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine University of Helsinki  Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"PERE","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine Helsinki University Hospital  Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,10,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/ael222"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aem332"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aen294"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/EJA.0b013e32834a11be"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000539-199504000-00014"},{"key":"e_1_2_7_7_1","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1213\/00000539-199903000-00010","article-title":"Anesthesia for in vitro fertilization: the addition of fentanyl to 1.5% lidocaine","volume":"88","author":"Martin R","year":"1999","journal-title":"Anesth Analg"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199709000-00014"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2006.01063.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-198910000-00009"},{"key":"e_1_2_7_11_1","first-page":"415","article-title":"Hypobaric bupivacaine spinal anesthesia for cystoscopic intervention: the impact of adding fentanyl","volume":"17","author":"Atallah MM","year":"2003","journal-title":"Middle East J Anesthesiol"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003006.pub3"},{"key":"e_1_2_7_13_1","first-page":"389","article-title":"Subarachnoid fentanyl augments lidocaine spinal anesthesia for cesarean delivery","volume":"20","author":"Palmer CM","year":"1995","journal-title":"Reg Anesth"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12630-009-9207-6"},{"key":"e_1_2_7_15_1","first-page":"600","article-title":"Intrathecal fentanyl added to hyperbaric ropivacaine for cesarean delivery","volume":"27","author":"Chung CJ","year":"2002","journal-title":"Reg Anesth Pain Med"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000539-200112000-00004"},{"key":"e_1_2_7_17_1","first-page":"203","article-title":"Inguinal hernia repair: anaesthesia, pain and convalescence","volume":"50","author":"Callesen T","year":"2003","journal-title":"Dan Med Bull"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9592.2010.03315.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00115550-200211000-00013"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-6576.2003.470103.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aen357"}],"container-title":["Acta Anaesthesiologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1399-6576.2012.02794.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1399-6576.2012.02794.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T07:13:12Z","timestamp":1697440392000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1399-6576.2012.02794.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,17]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["10.1111\/j.1399-6576.2012.02794.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1399-6576.2012.02794.x","archive":["Portico"],"relation":{},"ISSN":["0001-5172","1399-6576"],"issn-type":[{"value":"0001-5172","type":"print"},{"value":"1399-6576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10,17]]}}}