{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T01:47:48Z","timestamp":1790819268101,"version":"4.1.0"},"reference-count":35,"publisher":"Frontiers Media SA","issue":"9","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":1543,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,9]]},"DOI":"10.1111\/j.1432-2277.2011.01282.x","type":"journal-article","created":{"date-parts":[[2011,6,11]],"date-time":"2011-06-11T12:53:31Z","timestamp":1307796811000},"page":"892-903","source":"Crossref","is-referenced-by-count":32,"title":["IL-6 and IL-10 in post-transplant lymphoproliferative disorders development and maintenance: a longitudinal study of cytokine plasma levels and T-cell subsets in 38 patients undergoing treatment"],"prefix":"10.3389","volume":"24","author":[{"given":"Carl","family":"Hinrichs","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylke","family":"Wendland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heiner","family":"Zimmermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"Eurich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth","family":"Neuhaus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Schlattmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Babel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanno","family":"Riess","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"G\u00e4rtner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis","family":"Anagnostopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Reinke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf Ulrich","family":"Trappe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2011,6,11]]},"reference":[{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB1|cit1","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1097\/00007890-199502270-00015","article-title":"An increased incidence of Epstein-Barr virus infection and lymphoproliferative disorder in young children on FK506 after liver transplantation","volume":"59","author":"Cox","year":"1995","journal-title":"Transplantation"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB2|cit2","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1097\/00007890-199912270-00006","article-title":"Posttransplant lymphoproliferative disorders in adult and pediatric renal transplant patients receiving tacrolimus-based immunosuppression","volume":"68","author":"Shapiro","year":"1999","journal-title":"Transplantation"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB3|cit3","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1097\/01.TP.0000146385.40108.2B","article-title":"Simultaneous development of lymphoma in recipients of renal transplants from a single donor: donor origin confirmed by human leukocyte antigen staining and microsatellite analysis","volume":"79","author":"Caillard","year":"2005","journal-title":"Transplantation"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB4|cit4","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1097\/TP.0b013e3181761659","article-title":"Prospective study of sequential reduction in immunosuppression, interferon alpha-2B, and chemotherapy for posttransplantation lymphoproliferative disorder","volume":"86","author":"Swinnen","year":"2008","journal-title":"Transplantation"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB5|cit5","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/S0140-6736(84)90994-2","article-title":"Reversibility of lymphomas and lymphoproliferative lesions developing under cyclosporin-steroid therapy","volume":"1","author":"Starzl","year":"1984","journal-title":"Lancet"},{"issue":"Suppl. 1","key":"10.1111\/j.1432-2277.2011.01282.x-BIB6|cit6","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1023\/A:1008396821609","article-title":"Diagnosis and treatment of transplant-related lymphoma","volume":"11","author":"Swinnen","year":"2000","journal-title":"Ann Oncol"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB7|cit7","doi-asserted-by":"crossref","first-page":"2901","DOI":"10.1111\/j.1600-6143.2005.01098.x","article-title":"Effect of anti-CD 20 antibody rituximab in patients with post-transplant lymphoproliferative disorder (PTLD)","volume":"5","author":"Oertel","year":"2005","journal-title":"Am J Transplant"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB8|cit8","doi-asserted-by":"crossref","first-page":"3053","DOI":"10.1182\/blood-2005-01-0377","article-title":"Efficacy and safety of rituximab in B-cell post-transplant lymphoproliferative disorders: results of a prospective multicentre phase II study","volume":"107","author":"Choquet","year":"2006","journal-title":"Blood"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB9|cit9","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.3324\/haematol.11360","article-title":"Prospective phase II trial of extended treatment with rituximab in patients with B-cell post-transplant lymphoproliferative disease","volume":"92","author":"Gonzalez-Barca","year":"2007","journal-title":"Haematologica"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB10|cit10","first-page":"100","article-title":"Sequential treatment with rituximab and CHOP chemotherapy in B-cell PTLD - moving forward to a first standard of care: results from a prospective International Multicenter Trial","volume":"114","author":"Trappe","year":"2009","journal-title":"ASH Annual Meeting Abstracts"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB11|cit11","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.1200\/JCO.1998.16.6.2052","article-title":"Posttransplant lymphoproliferative disorders not associated with Epstein-Barr virus: a distinct entity?","volume":"16","author":"Leblond","year":"1998","journal-title":"J Clin Oncol"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB12|cit12","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1146\/annurev.med.56.082103.104727","article-title":"Post-transplant lymphoproliferative disorders","volume":"56","author":"Gottschalk","year":"2005","journal-title":"Annu Rev Med"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB13|cit13","doi-asserted-by":"crossref","first-page":"4101","DOI":"10.1182\/blood-2005-10-4160","article-title":"Cytokine polymorphisms in the Th1\/Th2 pathway and susceptibility to non-Hodgkin lymphoma","volume":"107","author":"Lan","year":"2006","journal-title":"Blood"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB14|cit14","doi-asserted-by":"crossref","first-page":"2806","DOI":"10.1172\/JCI116523","article-title":"Interleukin-6 production in posttransplant lymphoproliferative disease","volume":"91","author":"Tosato","year":"1993","journal-title":"J Clin Invest"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB15|cit15","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1097\/00041552-199307000-00018","article-title":"OKT3 monoclonal antibodies induce interleukin-6 and interleukin-10: a possible cause of lymphoproliferative disorders associated with transplantation","volume":"2","author":"Swinnen","year":"1993","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB16|cit16","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1097\/00007890-199903270-00015","article-title":"Interleukin-10 and posttransplant lymphoproliferative disorder after kidney transplantation","volume":"67","author":"Birkeland","year":"1999","journal-title":"Transplantation"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB17|cit17","doi-asserted-by":"crossref","first-page":"1590","DOI":"10.1182\/blood.V97.6.1590","article-title":"Treatment of B-lymphoproliferative disorder with a monoclonal anti-interleukin-6 antibody in 12 patients: a multicenter phase 1-2 clinical trial","volume":"97","author":"Haddad","year":"2001","journal-title":"Blood"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB18|cit18","first-page":"61","article-title":"Epstein-Barr virus, infectious mononucleosis, and posttransplant lymphoproliferative disorders","volume":"4","author":"Nalesnik","year":"1994","journal-title":"Transplant Sci"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB19|cit19","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1038\/sj.gene.6363645","article-title":"Cytokine gene polymorphism in human disease: on-line databases","volume":"1","author":"Bidwell","year":"1999","journal-title":"Genes Immun"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB20|cit20","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1097\/01.tp.0000269617.60751.c4","article-title":"Evidence for genetic susceptibility towards development of posttransplant lymphoproliferative disorder in solid organ recipients","volume":"84","author":"Babel","year":"2007","journal-title":"Transplantation"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB21|cit21","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1046\/j.1365-2141.2003.04540.x","article-title":"Epstein-Barr virus (EBV) load and interleukin-10 in EBV-positive and EBV-negative post-transplant lymphoproliferative disorders","volume":"122","author":"Muti","year":"2003","journal-title":"Br J Haematol"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB22|cit22","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1080\/10428190500160272","article-title":"Significance of Epstein-Barr virus (EBV) load and interleukin-10 in post-transplant lymphoproliferative disorders","volume":"46","author":"Muti","year":"2005","journal-title":"Leuk Lymphoma"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB23|cit23","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1080\/10428190400027837","article-title":"Epstein-Barr viral load, interleukin-6 and interleukin-10 levels in post-transplant lymphoproliferative disease: a nested case-control study in a renal transplant cohort","volume":"46","author":"Baiocchi","year":"2005","journal-title":"Leuk Lymphoma"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB24|cit24","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1097\/00007890-200208150-00017","article-title":"Constitutive activation of Jak\/STAT proteins in Epstein-Barr virus-infected B-cell lines from patients with posttransplant lymphoproliferative disorder","volume":"74","author":"Nepomuceno","year":"2002","journal-title":"Transplantation"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB25|cit25","first-page":"932","article-title":"Sequential treatment with the anti-CD 20 antibody rituximab and CHOP\u2003+\u2003GCSF chemotherapy in patients with post-transplant lymphoproliferative disorder (PTLD): first results of a multicenter phase II study","volume":"106","author":"Trappe","year":"2005","journal-title":"Blood (ASH Annual Meeting Abstracts)"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB26|cit26","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1182\/blood.V110.11.390.390","article-title":"Sequential treatment with rituximab and CHOP chemotherapy in B-cell PTLD - a new standard in therapy?","volume":"110","author":"Trappe","year":"2007","journal-title":"Blood"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB27|cit27","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1137\/0915079","article-title":"Computing Gaussian likelihoods and their derivatives for general linear mixed models","volume":"15","author":"Wolfinger","year":"1994","journal-title":"SIAM J Sci Comput"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB28|cit28","doi-asserted-by":"crossref","first-page":"481","DOI":"10.3109\/10428190009059266","article-title":"The role of cytokines in the pathogenesis and management of AIDS-related lymphomas","volume":"38","author":"Fassone","year":"2000","journal-title":"Leuk Lymphoma"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB29|cit29","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/1471-2407-7-35","article-title":"Growth regulation of simian and human AIDS-related non-Hodgkin\u2019s lymphoma cell lines by TGF-beta1 and IL-6","volume":"7","author":"Ruff","year":"2007","journal-title":"BMC Cancer"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB30|cit30","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S1470-2045(05)70434-4","article-title":"Genetic variation in TNF and IL10 and risk of non-Hodgkin lymphoma: a report from the InterLymph Consortium","volume":"7","author":"Rothman","year":"2006","journal-title":"Lancet Oncol"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB31|cit31","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.mehy.2005.01.005","article-title":"The link between T helper balance and lymphoproliferative disease","volume":"65","author":"Yun","year":"2005","journal-title":"Med Hypotheses"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB32|cit32","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.trim.2006.10.006","article-title":"Quantitative analysis of EBV-specific CD4\/CD8 T cell numbers, absolute CD4\/CD8 T cell numbers and EBV load in solid organ transplant recipients with PLTD","volume":"17","author":"Sebelin-Wulf","year":"2007","journal-title":"Transpl Immunol"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB33|cit33","doi-asserted-by":"crossref","first-page":"500","DOI":"10.4049\/jimmunol.163.1.500","article-title":"Endogenous CD8+ T cell expansion during regression of monoclonal EBV-associated posttransplant lymphoproliferative disorder","volume":"163","author":"Khatri","year":"1999","journal-title":"J Immunol"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB34|cit34","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1086\/315791","article-title":"Longitudinal dynamics of Epstein-Barr virus-specific cytotoxic T lymphocytes during posttransplant lymphoproliferative disorder","volume":"182","author":"Kuzushima","year":"2000","journal-title":"J Infect Dis"},{"key":"10.1111\/j.1432-2277.2011.01282.x-BIB35|cit35","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1097\/00007890-200110270-00012","article-title":"Complete regression of posttransplant lymphoproliferative disease using partially HLA-matched Epstein Barr virus-specific cytotoxic T cells","volume":"72","author":"Haque","year":"2001","journal-title":"Transplantation"}],"container-title":["Transplant International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1432-2277.2011.01282.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/j.1432-2277.2011.01282.x\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T09:46:45Z","timestamp":1686131205000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1432-2277.2011.01282.x"}},"subtitle":["Cytokine plasma levels during treatment of PTLD"],"short-title":[],"issued":{"date-parts":[[2011,6,11]]},"references-count":35,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2011,9]]}},"URL":"https:\/\/doi.org\/10.1111\/j.1432-2277.2011.01282.x","relation":{},"ISSN":["0934-0874"],"issn-type":[{"value":"0934-0874","type":"print"}],"subject":[],"published":{"date-parts":[[2011,6,11]]}}}