{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T20:02:15Z","timestamp":1760644935918},"reference-count":42,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2004,1,30]],"date-time":"2004-01-30T00:00:00Z","timestamp":1075420800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anat Histol Embryol"],"published-print":{"date-parts":[[2004,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The distributions and frequencies of some endocrine cells in the eight portions of the gastrointestinal tract (GIT) of BALB\/c mouse were studied. Endocrine cells were stained using immunohistochemical method with seven types of antisera against bovine chromogranin (BCG), serotonin, gastrin, cholecystokinin (CCK)\u20108, somatostatin, glucagon and human pancreatic polypeptide (HPP), and the regional distributions and their relative frequencies were observed in the eight portions of the GIT of BALB\/c mice. All seven types of immunoreactive (IR) cells were identified. Most of the IR cells in the intestinal portion were generally spherical or spindle in shape (open type cell) while round\u2010shaped cells (closed type cell) were found in the intestinal gland and stomach regions occasionally. Their relative frequencies varied according to each portion of the GIT. BCG\u2010IR cells were observed throughout the whole GIT except for the rectum and they were most predominant in the pylorus. Serotonin\u2010IR cells were detected throughout the whole GIT and they showed the highest frequency in the fundus. Gastrin\u2010 and CCK\u2010IR cells were restricted to the pylorus and duodenum with a majority in the pylorus and rare or a few frequencies in the duodenum. Compared with other mammals, somatostatin\u2010IR cells were restricted to the fundus and pylorus with a few frequencies, respectively. In addition, glucagon\u2010 and HPP\u2010IR cells were restricted to the fundus and duodenum, respectively, with relative low frequencies. Some species\u2010dependent unique distributions and frequencies of endocrine cells were observed in the GIT of BALB\/c mouse compared with other rodents.<\/jats:p>","DOI":"10.1111\/j.1439-0264.2004.00508.x","type":"journal-article","created":{"date-parts":[[2004,12,18]],"date-time":"2004-12-18T01:55:36Z","timestamp":1103334936000},"page":"42-48","source":"Crossref","is-referenced-by-count":11,"title":["An Immunohistochemical Study of Gastrointestinal Endocrine Cells in the BALB\/c Mouse"],"prefix":"10.1111","volume":"33","author":[{"given":"S. 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