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Immunoreactivities to chromogranin A, 5\u2010hydroxytryptamine, somatostatin, [met]\u2010 and [leu]\u2010 enkephalins, gastrin\u2010releasing peptide, calcitonin gene\u2010related peptide, neuropeptide Y, substance P, vasoactive intestinal peptide, <jats:italic>\u03b2<\/jats:italic>\u2010endorphin antisera were tested by a streptavidin\u2010biotin method. In the testis, epididymis, ductus deferens and vesicular gland no endocrine cells were found in any of the animals studied. Chromogranin\u2010A, serotonin, somatostatin and enkephalins were present in endocrine\/paracrine cells in the surface or glandular epithelia, whereas all other antisera gave negative results. In the prostatic complex and the urethral epithelium, the most consistent number of endocrine cells was serotonin\u2010immunoreactive. Few cells were also argentaffin and a very limited number of them showed argyrophily and chromogranin\u2010A immunoreactivity. Somatostatin\u2010and enkephalin\u2010immunoreactive cells were rare in the bull and boar, absent in stallions. This comparative study carried out on different species of domestic ungulates has shown deeply different immunophenotypes, even comparing species that are in a very close zoological relationship with one another, such as the horse and the donkey.<\/jats:p>","DOI":"10.1111\/j.1439-0264.2004.00541.x","type":"journal-article","created":{"date-parts":[[2004,7,6]],"date-time":"2004-07-06T11:02:20Z","timestamp":1089111740000},"page":"225-232","source":"Crossref","is-referenced-by-count":13,"title":["Endocrine\u2010Paracrine Cells of the Male Urogenital Apparatus: a Comparative Histochemical and Immunohistochemical Study in some Domestic Ungulates"],"prefix":"10.1111","volume":"33","author":[{"given":"S.","family":"Arrighi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Cremonesi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Bosi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Domeneghini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,7,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1677\/erc.0.0060503"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0045(20010215)46:3<191::AID-PROS1023>3.0.CO;2-D"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0045(19970915)33:1<18::AID-PROS4>3.0.CO;2-5"},{"key":"e_1_2_6_5_1","first-page":"12","article-title":"Presence of endocrine\u2010like cells producing regulatory peptides and biogenic amines in the male urogenital apparatus of some domestic mammals. 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