{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T15:43:42Z","timestamp":1762098222337},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,1,13]],"date-time":"2005-01-13T00:00:00Z","timestamp":1105574400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anat Histol Embryol"],"published-print":{"date-parts":[[2005,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The microstructural and ultrastructural features of the equine lingual tonsil were studied in five young horses. Located at the root of the tongue it presented an irregular surface with rounded elevations, numerous folds and crypts. Stratified squamous non\u2010keratinized epithelium lining its outer surface was modified by heavy infiltration of lymphoid cells to form reticular epithelium within the crypt. The latter implies a role in initiating and maintaining immune responses to incoming infectious agents and antigens. Lamellated structures resembling Hassall's corpuscle were observed towards the outer surface epithelium. Microplicae were visible by scanning electron microscopy on the surface of both the outer and reticular epithelia. No microvillus cells resembling M cells were observed. The stratum superficiale of the reticular epithelium showed strong affinity for <jats:italic>Soybean<\/jats:italic> (SBA), <jats:italic>Phosphocarpus tetragonolobus<\/jats:italic> 1 (WBA 1), <jats:italic>Ulex europaeus<\/jats:italic> (UEA) and <jats:italic>Griffonia simplicifolia<\/jats:italic> 1 isolectin\u2010B4 (GS1\u2010B4). The characteristic lectin binding patterns may be useful for embryological and microbiological investigations. Vimentin filaments were not detected consistent with absence of M cells. Mucus glandular acini in the deeper lamina propria mucosae contained glycogen, acidic, neutral and weakly sulphated mucopolysaccharides. Transmission electron microscopy revealed that the layers of the outer surface and reticular epithelia shared characteristic features except the stratum superficiale, which had nuclei of varying shapes and an abundance of cell organelles. A few mast cells with electron lucent granules and myelinated nerve fibres were localized in the deeper portion.<\/jats:p>","DOI":"10.1111\/j.1439-0264.2004.00560.x","type":"journal-article","created":{"date-parts":[[2005,1,13]],"date-time":"2005-01-13T17:10:49Z","timestamp":1105636249000},"page":"27-33","source":"Crossref","is-referenced-by-count":15,"title":["Histology and Ultrastructure of the Equine Lingual Tonsil. I. Crypt Epithelium and Associated Structures"],"prefix":"10.1111","volume":"34","author":[{"given":"P.","family":"Kumar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. F.","family":"Timoney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,1,13]]},"reference":[{"key":"e_1_2_15_2_1","first-page":"64","volume-title":"Advances in Oto\u2010Rhino\u2010Laryngology, Vol. 47, A Clinically Oriented Update","author":"Brandtzaeg P.","year":"1992"},{"key":"e_1_2_15_3_1","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/s004180000198","article-title":"Differential cytokeratin and glycoconjugate expression by the surface and crypt epithelia of human palatine tonsils","volume":"114","author":"Clark M. A.","year":"2000","journal-title":"Histochem. 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