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The distribution of anti\u2010microbial substances in the submandibular glands of Japanese miniature (Shiba) goat was studied using immunohistochemical methods as performed by physical development procedures. In the goat, anti\u2010microbial substances such as lysozyme, IgA, lactoferrin and \u03b2\u2010defensin were demonstrated to be immunolocalized in the submandibular glands, especially in the serous demilunes and duct cells. The results obtained are discussed with regard to the specific functions of the saliva. The presence and secretion of anti\u2010microbial substances suggest that they participate in the maintenance of oral health among the elements of saliva.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1439-0264.2011.01102.x","type":"journal-article","created":{"date-parts":[[2011,9,6]],"date-time":"2011-09-06T04:53:26Z","timestamp":1315284806000},"page":"54-59","source":"Crossref","is-referenced-by-count":4,"title":["Immunohistochemical Aspects of Anti\u2010microbial Properties in Goat Submandibular Glands"],"prefix":"10.1111","volume":"41","author":[{"given":"I.","family":"Habata","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Yasui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Fujimori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Tsukise","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,9,6]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.2174\/138161207782110417"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-302X.1999.140607.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0738-081X(00)00174-7"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.112.4.1553"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01002902"},{"key":"e_1_2_5_7_1","first-page":"121","article-title":"Structural characteristics of goat (Capra hircus) parotid salivary glands","volume":"58","author":"Elewa Y. 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