{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T20:26:01Z","timestamp":1764102361942},"reference-count":24,"publisher":"Wiley","issue":"7-8","license":[{"start":{"date-parts":[[2005,4,4]],"date-time":"2005-04-04T00:00:00Z","timestamp":1112572800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2005,8]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The effect of intraileally infused short chain fatty acids (SCFA) and saline as control on the exocrine pancreatic secretions during the interdigestive phase was studied using three 8\u2010weeks\u2010old piglets. Pigs were surgically fitted with a pancreatic duct catheter, re\u2010entrant duodenal T\u2010cannula for collection and subsequent return of pancreatic juice, and with an infusion T\u2010cannula at the distal ileum. Saline as control, 5.0 and 10.0\u2003m<jats:sc>m<\/jats:sc> butyrate, 7.5 and 15.0\u2003m<jats:sc>m<\/jats:sc> propionate and 85.0 and 170.0\u2003m<jats:sc>m<\/jats:sc> acetate were infused at 2\u2003ml\/kg body weight (BW) for 30\u2003min into the ileum of overnight fasted piglets via ileal T\u2010cannula. The calculated volume of infusates was administrated in five equal bolus at 6\u2003min intervals over a period of 30\u2003min. The pancreatic juice was collected 60 and 30\u2003min before and 30, 60, 90 and 120\u2003min after the start of infusion. The trypsin (p\u2003=\u20030.07, p\u2003&gt;\u20030.15 respectively) and protein (p\u2003&gt;\u20030.15, p\u2003=\u20030.05 respectively) outputs immediately decreased after the infusion of acetate at the dose of 85.0 and 170.0\u2003m<jats:sc>m<\/jats:sc>, respectively, whereas pancreatic juice outflow (p\u2003&gt;\u20030.15) was not significantly affected when compared with levels 30\u2003min before infusion. After the infusion of butyrate at the dose of 5.0\u2003m<jats:sc>m<\/jats:sc>, trypsin (p\u2003=\u20030.01) and protein (p\u2003=\u20030.12) outputs increased immediately whereas pancreatic juice outflow was not affected (p\u2003&gt;\u20030.15) in comparison with levels 30\u2003min before infusion. No significant differences were observed after infusion of butyrate at the dose of 10\u2003m<jats:sc>m<\/jats:sc> for the pancreatic juice outflow, trypsin and protein outputs when compared with the level before infusion, although these values were numerically lower immediately after the infusion. The pancreatic juice outflow increased (p\u2003=\u20030.03) after the infusion of propionate at the dose of 7.5\u2003m<jats:sc>m<\/jats:sc> and decreased (p\u2003=\u20030.005) immediately after the infusion of propionate at the dose of 15.0\u2003m<jats:sc>m<\/jats:sc> when compared with the levels 30\u2003min before the infusions. After the infusion of propionate at the dose of 7.5 or 15.0\u2003m<jats:sc>m<\/jats:sc> for the output of protein and trypsin, no significant differences (p\u2003&gt;\u20030.15) were observed when compared with levels 30\u2003min before infusion. In summary, the intraileal infusion of SCFA at different doses exerts a short\u2010term and moderate effect on the interdigestive exocrine pancreatic secretions in pigs.<\/jats:p>","DOI":"10.1111\/j.1439-0396.2005.00511.x","type":"journal-article","created":{"date-parts":[[2005,6,22]],"date-time":"2005-06-22T12:33:20Z","timestamp":1119443600000},"page":"253-259","source":"Crossref","is-referenced-by-count":11,"title":["Effect of short chain fatty acids infused intraileally on interdigestive exocrine pancreatic secretions in growing pigs"],"prefix":"10.1111","volume":"89","author":[{"given":"V.","family":"Sileikiene","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Mosenthin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Tafaj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Kruszewska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Westr\u00f6m","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Mattsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. 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