{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T07:17:11Z","timestamp":1791011831674,"version":"4.1.0"},"reference-count":47,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2008,5,15]],"date-time":"2008-05-15T00:00:00Z","timestamp":1210809600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2009,8]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Alterations of the phospholipid (PL) compositions of body fluids are assumed to be indicative of inflammatory diseases, e.g. rheumatoid arthritis (RA). Recently, we have shown that particularly the phosphatidylcholine\/lysophosphatidylcholine (PC\/LPC) ratio determined in human synovial fluids (SF) and sera represents a reliable measure of the inflammatory state in RA patients. However, it is not yet clear to what extent the PC\/LPC ratio is also affected by nutrition habits. In the present study, the PL and the corresponding acyl chain compositions of human body fluids (SF and serum of RA patients as well as serum from healthy volunteers) are compared with those of two other mammalian species (horses and dogs suffering from degenerative joint diseases as well as healthy controls) by high\u2010resolution <jats:sup>31<\/jats:sup>P\u2010nuclear magnetic resonance (NMR) spectroscopy and matrix\u2010assisted laser desorption and ionization time\u2010of\u2010flight mass spectrometry (MALDI\u2010TOF MS). The most important result of this study is that the PL compositions of SF and serum of horse and dog are comparable with those of human body fluids. Compared with humans, however, the horse body fluid contains less PCs with highly unsaturated arachidonoyl residues, while that of dogs possesses the highest content of arachidonoyl\u2010containing PC. These species\u2010related differences stem primarily from different nutrition habits (meat vs. plants).<\/jats:p>","DOI":"10.1111\/j.1439-0396.2008.00822.x","type":"journal-article","created":{"date-parts":[[2008,5,15]],"date-time":"2008-05-15T16:18:47Z","timestamp":1210868327000},"page":"410-422","source":"Crossref","is-referenced-by-count":29,"title":["Phospholipid compositions of sera and synovial fluids from dog, human and horse: a comparison by <sup>31<\/sup>P\u2010NMR and MALDI\u2010TOF MS"],"prefix":"10.1111","volume":"93","author":[{"given":"B.","family":"Fuchs","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Bondzio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U.","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Schiller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,7,8]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000068906"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.858"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0271-5317(97)00053-5"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/128.12.2641S"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1139\/y59-099"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1582-4934.2003.tb00203.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1984.tb01883.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1995.tb03079.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-2427(99)00054-9"},{"key":"e_1_2_6_11_1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1097\/00006205-199102000-00003","article-title":"Evaluating arthritic complaints","volume":"16","author":"Collo M. C.","year":"1991","journal-title":"Nurse Practitioner"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/jms.759"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/jms.603"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2005.06.006"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbbm.2007.03.001"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-007-1488-4"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11745-007-3108-7"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.04-1155"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.57.9.550"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0005-2760(98)00005-8"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11745-006-5014-9"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/0305-0491(95)02011-X"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.2527\/jas.2006-528"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.3109\/17453679809117617"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/1522-2594(200008)44:2<215::AID-MRM8>3.0.CO;2-N"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/bmc.563"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00537a007"},{"key":"e_1_2_6_28_1","first-page":"211","article-title":"Phospholipase A2 activity in sera and synovial fluids in rheumatoid arthritis and osteoarthritis. Its possible role as a proinflammatory enzyme","volume":"12","author":"Pruzanski W.","year":"1985","journal-title":"Journal of Rheumatology"},{"key":"e_1_2_6_29_1","first-page":"117","article-title":"The role of phospholipase A2 in the physiopathology of osteoarthritis","volume":"18","author":"Pruzanski W.","year":"1991","journal-title":"Journal of Rheumatology"},{"key":"e_1_2_6_30_1","first-page":"161","article-title":"Secretory non\u2010pancreatic proup II phospholipase A2: role in physiologic and inflammatory processes","volume":"8","author":"Pruzanski W.","year":"1993","journal-title":"Journal of Lipid Mediators and Cell Signalling"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/82.2.327"},{"key":"e_1_2_6_32_1","first-page":"559","volume-title":"Encyclopedia of Analytical Chemistry","author":"Schiller J.","year":"2000"},{"key":"e_1_2_6_33_1","first-page":"205","article-title":"Application of high resolution 31P NMR spectroscopy to the characterization of the phospholipid composition of tissues and body fluids \u2013 a methodological review","volume":"8","author":"Schiller J.","year":"2002","journal-title":"Medical Science Monitor"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1006\/abio.1998.3001"},{"key":"e_1_2_6_35_1","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1016\/S0022-2275(20)34196-1","article-title":"Lipid analysis of human HDL and LDL by MALDI\u2010TOF mass spectrometry and 31P\u2010NMR","volume":"42","author":"Schiller J.","year":"2001","journal-title":"Journal of Lipid Research"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-3084(01)00188-8"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.2174\/0929867033456828"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plipres.2004.08.001"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.2174\/138527206778249856"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.2174\/157341107782109635"},{"key":"e_1_2_6_41_1","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0022-2275(20)37640-9","article-title":"Comparative studies on the substrate specificity of lecithin: cholesterol acyltransferase towards the molecular species of phosphatidylcholine in the plasma of 14 vertebrates","volume":"37","author":"Subbaiah P. V.","year":"1996","journal-title":"Journal of Lipid Research"},{"key":"e_1_2_6_42_1","doi-asserted-by":"crossref","first-page":"1086S","DOI":"10.1093\/jn\/126.suppl_4.1086S","article-title":"Antagonistic effects of dietary arachidonic acid and n\u20103 polyunsaturated fatty acids","volume":"126","author":"Whelan J.","year":"1996","journal-title":"Journal of Nutrition"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/28.1.23"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1997.0328a.x"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/0305-0491(79)90309-2"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemphyslip.2003.12.003"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1080\/00032710600620484"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2736(95)00180-5"}],"container-title":["Journal of Animal Physiology and Animal Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1439-0396.2008.00822.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1439-0396.2008.00822.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T22:37:15Z","timestamp":1696891035000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1439-0396.2008.00822.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7,8]]},"references-count":47,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,8]]}},"alternative-id":["10.1111\/j.1439-0396.2008.00822.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1439-0396.2008.00822.x","archive":["Portico"],"relation":{},"ISSN":["0931-2439","1439-0396"],"issn-type":[{"value":"0931-2439","type":"print"},{"value":"1439-0396","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,7,8]]}}}