{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T21:27:21Z","timestamp":1790198841927,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,7,18]],"date-time":"2011-07-18T00:00:00Z","timestamp":1310947200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animal Physiology Nutrition"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Feline chronic gingivitis\/stomatitis (FCGS) is a painful inflammatory disease in cats. Extraction of teeth, including all premolars and molars, has been shown to be the therapy of choice in cats not responding sufficiently to home care (e.g. tooth brushing) and\/or medical treatment (corticosteroids and\/or antibiotics). In this study, we hypothesize that a cat food with an omega\u20106 polyunsaturated fatty acid (\u03c96 PUFA) to \u03c93 PUFA ratio of 10:1 reduces inflammation of the FCGS and accelerates soft tissue wound healing of the gingiva after dental extractions, compared to a cat food with a \u03c96:\u03c93 PUFA ratio of 40:1. The cats were fed diets with chicken fat and fish oil as sources of fatty acids. In one diet, part of the fish oil was replaced by safflower oil, resulting in two diets with \u03c96:\u03c93 PUFA ratios of 10:1 and 40:1. This double\u2010blinded study in two groups of seven cats revealed that dietary fatty acids influence the composition of plasma cholesteryl esters and plasma levels of inflammatory cytokines. The diet with the 10:1 ratio lowered PGD<jats:sub>2<\/jats:sub>, PGE<jats:sub>2<\/jats:sub>and LTB<jats:sub>4<\/jats:sub>plasma levels significantly, compared to the diet with the 40:1 ratio (p\u2003=\u20030.05, p\u2003=\u20030.04, and p\u2003=\u20030.02 respectively). However, feeding diets with dietary \u03c96:\u03c93 PUFA ratios of 10:1 and 40:1, given to cats with FCGS for 4\u2003weeks after extraction of all premolars and molars, did not alter the degree of inflammation or wound healing.<\/jats:p>","DOI":"10.1111\/j.1439-0396.2011.01195.x","type":"journal-article","created":{"date-parts":[[2011,7,18]],"date-time":"2011-07-18T10:48:14Z","timestamp":1310986094000},"page":"671-680","source":"Crossref","is-referenced-by-count":16,"title":["Inflammation and wound healing in cats with chronic gingivitis\/stomatitis after extraction of all premolars and molars were not affected by feeding of two diets with different omega\u20106\/omega\u20103 polyunsaturated fatty acid ratios"],"prefix":"10.1111","volume":"96","author":[{"given":"R. J.","family":"Corbee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. E.","family":"Booij\u2010Vrieling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. H. A.","family":"van de Lest","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. C.","family":"Penning","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. A.","family":"Tryfonidou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. M.","family":"Riemers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. A. 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