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In addition, abdominal alopecia, thin and inelastic skin, weight loss despite polyphagia, polyuria and polydipsia were present. Laboratory investigation revealed diabetes mellitus and pituitary\u2010dependent hypercortisolism. Diagnostic imaging showed bilaterally enlarged adrenals and a large pituitary mass. Histopathological and immunohistochemical examination confirmed the clinical diagnosis of an ACTH\u2010producing pituitary macroadenoma.<\/jats:p>","DOI":"10.1111\/j.1439-0442.2007.00962.x","type":"journal-article","created":{"date-parts":[[2007,8,21]],"date-time":"2007-08-21T03:46:06Z","timestamp":1187667966000},"page":"359-363","source":"Crossref","is-referenced-by-count":18,"title":["Pituitary Macroadenoma in a Cat with Diabetes Mellitus, Hypercortisolism and Neurological Signs"],"prefix":"10.1111","volume":"54","author":[{"given":"F.","family":"Fracassi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Mandrioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Diana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Hilbe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Grinwis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Gandini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,8,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.3892690"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0739-7240(02)00128-5"},{"key":"e_1_2_7_4_1","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.2460\/javma.1995.207.08.1066","article-title":"Adrenalectomy for treatment of hyperadrenocorticism in cats: 10 cases (1988\u20131992)","volume":"207","author":"Duesberg C. 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