{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T05:26:51Z","timestamp":1791178011306,"version":"4.1.0"},"reference-count":70,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2006,8,23]],"date-time":"2006-08-23T00:00:00Z","timestamp":1156291200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Veterinary Medicine, Series B"],"published-print":{"date-parts":[[2006,9]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Shiga toxin (Stx) [Verotoxin (VT)]\u2010producing <jats:italic>Escherichia coli<\/jats:italic> (STEC), also called enterohaemorrhagic <jats:italic>E. coli<\/jats:italic> or VTEC are emerging zoonotic agents and became most important as human pathogens, particularly in the industrialized countries. Production of cytotoxins, also called Stx or VT, is the major pathogenicity determinant of STEC, which can cause life\u2010threatening haemorrhagic diseases in humans. The spectrum of STEC phenotypes is diverse and domestic and wildlife animals constitute important reservoirs for these bacteria. STEC are spread from animal faeces to the environment, water and food. Ingestion of contaminated foodstuff and water, as well as contact with the environment, STEC\u2010excreting animals or humans are the major sources of human infection. Economical changes in animal and food production, alteration of consumer habits and lack of specific immune response, particularly in urbanized populations, have contributed to the recent spread of STEC as a zoonotic agent. Supranational surveillance networks as well as national reference laboratories as sentinels play an important role in the prevention and control of STEC infections in humans. Development of new vaccines and probiotics may serve as future tools to control the spread of STEC in animals and humans.<\/jats:p>","DOI":"10.1111\/j.1439-0450.2006.00968.x","type":"journal-article","created":{"date-parts":[[2006,8,29]],"date-time":"2006-08-29T15:03:18Z","timestamp":1156863798000},"page":"299-305","source":"Crossref","is-referenced-by-count":100,"title":["Emerging Enterohaemorrhagic <i>Escherichia coli<\/i>, Causes and Effects of the Rise of a Human Pathogen"],"prefix":"10.1111","volume":"53","author":[{"given":"L.","family":"Beutin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,8,23]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.73.10.6608-6619.2005"},{"key":"e_1_2_12_3_1","first-page":"1","volume-title":"Report of WHO Working Group Meeting on Shiga\u2010like Toxin producing Escherichia coli (SLTEC), with Emphasis on Zoonotic Aspects","author":"Anonymous","year":"1995"},{"key":"e_1_2_12_4_1","volume-title":"WHO Consulation on Selected Emerging Foodborne Diseases, Berlin, Germany 20\u201324 March 1995","author":"Anonymous","year":"1996"},{"key":"e_1_2_12_5_1","first-page":"1","volume-title":"Prevention and Control of Enterohaemorrhagic Escherichia coli (EHEC) Infections","author":"Anonymous","year":"1997"},{"key":"e_1_2_12_6_1","first-page":"1","volume-title":"Zoonotic Non\u2010O157 Shiga Toxin\u2010producing Escherichia coli (STEC)","author":"Anonymous","year":"1998"},{"key":"e_1_2_12_7_1","first-page":"1","volume-title":"Zoonoses Report, United Kingdom 2003","author":"Anonymous","year":"2004"},{"key":"e_1_2_12_8_1","first-page":"392","article-title":"Preliminary FoodNet data on the incidence of infection with pathogens transmitted commonly through food \u2013 10 states, United States, 2005","volume":"55","author":"Anonymous","year":"2006","journal-title":"Morb. 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