{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T06:28:54Z","timestamp":1770964134025,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"s1","license":[{"start":{"date-parts":[[2009,4,24]],"date-time":"2009-04-24T00:00:00Z","timestamp":1240531200000},"content-version":"vor","delay-in-days":4406,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[1997,4]]},"abstract":"<jats:p><jats:bold>Zusammenfassung. <\/jats:bold> Da Schw\u00e4rzepilze zu den seltenen Erregern von Mykosen z\u00e4hlen, begr\u00fcnden sich Therapieempfehlungen vorwiegend auf Einzelfallbeobachtungen. Bei Eumyzetomen und herdf\u00f6rmigen Phaeohyphomykosen des Zentralnervensystems (z. B. durch <jats:italic>Cladophialophora bantiana, Exophiala dermatitidis<\/jats:italic>) und in bestimmten F\u00e4llen einer Chromoblastomykose ist die Resektion in toto Therapie der Wahl, ggf. mit antimykotischer Begleitmedikation. Zur antimykotischen Therapie ex juvantibus bei Phaeohyphomykosen ist z. Z. ein Therapicerfolg mit einer Kombinationsbehandiung aus Itraconzol und 5\u2010Fluorcytosin am ehesten zu erwatten. Eine ausreichende Therapiedauer ist f\u00fcr den Erfolg ma\u00dfgebend.<\/jats:p><jats:p><jats:bold>Summary. <\/jats:bold> Since dematiaceous fungi belong to the group of rare infectious agents causing mycoses, therapeutic recommendations are mainly deduced from observations of single cases. In cases of eumycetoma or focal phaeohyphomycoses of the central nervous system (e.g. caused by <jats:italic>Cladophialophora bantiana<\/jats:italic> or <jats:italic>Exophiala dermatitidis<\/jats:italic>) and in certain cases of chromoblastomycoses, the resection in loto is the therapy of choice, which may be accompanied by antimycotic medication. As antimycotic therapy ex juvantibus in case of phaeohyphomycoses, a simultaneous application of itraconazole and 5\u2010fluorocytosine is presently most promising. The success depends on an adequate duration of therapy.<\/jats:p>","DOI":"10.1111\/j.1439-0507.1997.tb00549.x","type":"journal-article","created":{"date-parts":[[2009,4,24]],"date-time":"2009-04-24T16:43:25Z","timestamp":1240591405000},"page":"91-96","source":"Crossref","is-referenced-by-count":8,"title":["Therapie von Infektionen durch Schw\u00e4rzepilze"],"prefix":"10.1111","volume":"40","author":[{"given":"Kathrin","family":"Tintelnot","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,4,24]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1111\/myc.1990.33.5.215","article-title":"Melanin as a virulence factor in pathogenic fungi","volume":"33","author":"Polak A.","year":"1989","journal-title":"Mycoses"},{"key":"e_1_2_1_3_2","first-page":"111","article-title":"Wenig beachtete Mykosen durch demati\u00f6se Opportunisten","volume":"19","author":"Tintelnot K.","year":"1991","journal-title":"Immun. 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