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In the second case, initial mycological tests on CSF (direct microscopy and culture) were repetitively negative and latex antigen tests gave unconvincing results. The patient was started on triple antituberculosis therapy, on which he improved immediately; therapy was continued for 1\u2003year with the patient remaining well. However, within 1\u2003week of stopping therapy, he had to be readmitted with neurological signs and symptoms. Culture of CSF this time yielded <jats:italic>Cryptococcus neoformans<\/jats:italic> and the antigen test was consistently positive. These are the first reported cases of cryptococcal meningitis in immunocompetent patients in Malta.<\/jats:p>","DOI":"10.1111\/j.1439-0507.2004.00963.x","type":"journal-article","created":{"date-parts":[[2004,12,27]],"date-time":"2004-12-27T17:21:37Z","timestamp":1104168097000},"page":"168-173","source":"Crossref","is-referenced-by-count":20,"title":["Cryptococcal meningitis in two apparently immunocompetent Maltese patients"],"prefix":"10.1111","volume":"47","author":[{"given":"L.","family":"Vella Zahra","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Mallia Azzopardi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Scott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,4,8]]},"reference":[{"key":"e_1_2_7_2_2","first-page":"397","volume-title":"Medical Mycology","author":"Kwon\u2010Chung KJ","year":"1992"},{"key":"e_1_2_7_3_2","first-page":"582","volume-title":"Medical Mycology. 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