{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:46:13Z","timestamp":1761630373644},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,4,13]],"date-time":"2005-04-13T00:00:00Z","timestamp":1113350400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2005,5]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Itraconazole is a systemic triazole with a broad\u2010spectrum antifungal effect which belongs to a standard choice for the treatment of vulvovaginal candidosis. Thirty\u2010four patients with acute and 26 patients with recurrent form of culture documented attacks of vulvovaginal candidosis were evaluated. There was frequent discrepancy between severe symptoms and weaker signs in patients with recurrent form than in the group with acute sporadic form. Eighteen patients with the acute form and 13 patients with the recurrent form of vulvovaginal candidosis received 1\u2010day therapy (twice 200\u2003mg of itraconazole in 1\u2003day). Sixteen patients with the acute form and 13 patients with the recurrent form received 3\u2010day therapy (200\u2003mg of itraconazole daily for three following days). The cure rates 1\u2003month after treatment were 97.1 and 76.9% in patients with the acute sporadic and recurrent form of vulvovaginal candidosis, respectively. Positive cultures in the latter group documented relapses. These clinical failures were not related to the resistance of yeasts to itraconazole. With the exception of one case of alopecia areata, side effects were minimal. The application of the long\u2010term regimens and suppressive therapy with azole drugs is suggested in patients with recurrent vulvovaginal candidosis.<\/jats:p>","DOI":"10.1111\/j.1439-0507.2005.01099.x","type":"journal-article","created":{"date-parts":[[2005,4,13]],"date-time":"2005-04-13T17:21:52Z","timestamp":1113412912000},"page":"165-171","source":"Crossref","is-referenced-by-count":10,"title":["Itraconazole in the treatment of acute and recurrent vulvovaginal candidosis: comparison of a 1\u2010day and a 3\u2010day 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