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Proper management requires recognition of the clinical syndromes caused by <jats:italic>Histoplasma capsulatum<\/jats:italic> infection, familiarity with the uses and limitations of the diagnostic tests, an understanding of the indications for treatment and role of specific antifungal agents. This review will address these issues with the goal of providing physicians in non\u2010endemic areas sufficient information to suspect, diagnose, and treat patients with histoplasmosis.<\/jats:p>","DOI":"10.1111\/j.1439-0507.2006.01253.x","type":"journal-article","created":{"date-parts":[[2006,6,16]],"date-time":"2006-06-16T11:09:59Z","timestamp":1150456199000},"page":"274-282","source":"Crossref","is-referenced-by-count":121,"title":["Histoplasmosis: a review for clinicians from non\u2010endemic areas"],"prefix":"10.1111","volume":"49","author":[{"given":"L.","family":"Joseph Wheat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,6,16]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"97","article-title":"Diagnostic usefulness of the intradermal test with histoplamin in non\u2010endemic areas of histoplasmosis","volume":"17","author":"Torres\u2010Rodriguez JM","year":"2000","journal-title":"Rev Iberoam Micol"},{"key":"e_1_2_5_3_2","first-page":"362","article-title":"Disseminated histoplasmosis in patients with AIDS. case reports","volume":"2","author":"Antinori S","year":"2000","journal-title":"Recenti Prog Med"},{"key":"e_1_2_5_4_2","first-page":"373","article-title":"Disseminated histoplasmosis 19 years after renal transplantation","volume":"51","author":"Jha V","year":"1999","journal-title":"Clin Nephrol"},{"key":"e_1_2_5_5_2","first-page":"231","article-title":"Cerebral miliary granulomatosis with Histoplasma capsulatum in an HIV seronegative patient","volume":"155","author":"Hadi M","year":"1999","journal-title":"Rev Neurol (Paris)"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/PL00002566"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.1998.tb00724.x"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.1997.00113.x"},{"key":"e_1_2_5_9_2","first-page":"210","article-title":"Acute pulmonary histoplasmosis with liver and lung involvement outside the endemic area\u2013differential diagnosis","volume":"108","author":"Armbruster C","year":"1996","journal-title":"Wien Klin Wochenschr"},{"key":"e_1_2_5_10_2","first-page":"679","article-title":"Intestinal histoplasmosis in AIDS patients: report of three cases observed in France and review of the literature","volume":"7","author":"Trylesinski A","year":"1995","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"e_1_2_5_11_2","first-page":"97","article-title":"Digestive histoplasmosis in a patient with AIDS from Guadeloupe","volume":"30","author":"Boulard F","year":"1994","journal-title":"Ann Gastroenterol Hepatol (Paris)"},{"key":"e_1_2_5_12_2","first-page":"234","article-title":"Disseminated histoplasmosis in AIDS. 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