{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T17:13:46Z","timestamp":1762017226435},"reference-count":0,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2007,7,18]],"date-time":"2007-07-18T00:00:00Z","timestamp":1184716800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2007,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p> <jats:italic>Scedosporium apiospermum<\/jats:italic> is an emerging fungal pathogen, increasingly recognised as a cause of infection not only in immunocompromised, but also in non\u2010immunodeficient patients. We present the case of an immunocompetent 21\u2010year\u2010old Thai man who experienced recurrent ruptured mycotic aneurysms and developed multiple <jats:italic>S. apiospermum<\/jats:italic> brain abscesses following aspiration of polluted water. A combination of surgery and voriconazole was effective in this difficult\u2010to\u2010treat case. Voriconazole penetrated the central nervous system (CNS) well and had limited toxicity, despite prolonged treatment. Voriconazole appears to be the antifungal agent of choice in the treatment of CNS scedosporiosis caused by <jats:italic>S<\/jats:italic>. <jats:italic>apiospermum<\/jats:italic>.<\/jats:p>","DOI":"10.1111\/j.1439-0507.2007.01410.x","type":"journal-article","created":{"date-parts":[[2007,7,18]],"date-time":"2007-07-18T10:35:28Z","timestamp":1184754928000},"page":"512-516","source":"Crossref","is-referenced-by-count":34,"title":["Multiple <i>Scedosporium apiospermum<\/i> brain abscesses after near\u2010drowning successfully treated with surgery and long\u2010term voriconazole: a case report"],"prefix":"10.1111","volume":"50","author":[{"given":"M.","family":"Leechawengwongs","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Milindankura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Liengudom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Chanakul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Viranuvatti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Clongsusuek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,7,29]]},"container-title":["Mycoses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1439-0507.2007.01410.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1439-0507.2007.01410.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T19:39:15Z","timestamp":1696880355000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1439-0507.2007.01410.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7,29]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007,11]]}},"alternative-id":["10.1111\/j.1439-0507.2007.01410.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1439-0507.2007.01410.x","archive":["Portico"],"relation":{},"ISSN":["0933-7407","1439-0507"],"issn-type":[{"value":"0933-7407","type":"print"},{"value":"1439-0507","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,7,29]]}}}