{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T16:23:38Z","timestamp":1788279818699,"version":"build-2803163510"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,7,20]],"date-time":"2011-07-20T00:00:00Z","timestamp":1311120000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2012,3]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    1\u20133% of human population is affected by psoriasis. Nail disorders are reported in 10\u201380% of patients with psoriasis. Nail deformations vary according to their degree of severity but are mainly represented by pitting, Beau\u2019s lines, hyperkeratosis, onycholysis, leuconychia or oil drops. Onychomycosis is a fungal infection of the nails, caused by dermatophytes, yeast and moulds. In this study, 228 patients with psoriasis aged between 18 and 72 were examined (48 \u2013 from Plovdiv, Bulgaria; 145 \u2013 from Pleven, Bulgaria and 35 \u2013 from Thessaloniki, Greece); 145 of them were male and 83 of them were female. The examination of the nail material was performed via direct microscopy with 20% KOH and nail samples plated out on Sabouraud agar methodology. The severity of the nail disorders was determined according to the Nail Psoriasis Severity Index (NAPSI). Positive mycological cultures were obtained from 62% of the patients with psoriasis (52%\u2013 Plovdiv, Bulgaria; 70%\u2013 Pleven, Bulgaria and 43%\u2013 Thessaloniki, Greece). In 67% of the cases, the infection was caused by dermatophytes, in 24% by yeast, in 6% by moulds and in 3% by a combination of causes. All patients with psoriasis were identified with high levels of NAPSI, whereas the ones with isolated\n                    <jats:italic>Candida<\/jats:italic>\n                    had even higher levels. Seventeen percentage of the patients have been treated with methotrexate, 6% have been diagnosed with diabetes and 22% have been reported with onychomycosis and tinea pedis within the family. An increased prevalence of onychomycosis among the patients with psoriasis was found. Dystrophic nails in psoriasis patients are more predisposed to fungal infections. The mycological examination of all psoriasis patients with nail deformations is considered obligatory because of the great number of psoriasis patients diagnosed with onychomycosis.\n                  <\/jats:p>","DOI":"10.1111\/j.1439-0507.2011.02053.x","type":"journal-article","created":{"date-parts":[[2011,7,20]],"date-time":"2011-07-20T06:17:15Z","timestamp":1311142635000},"page":"143-147","source":"Crossref","is-referenced-by-count":44,"title":["Onychomycosis in patients with psoriasis \u2013 a multicentre study"],"prefix":"10.1111","volume":"55","author":[{"given":"L.","family":"Zisova","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Valtchev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Sotiriou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Gospodinov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Mateev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,7,20]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"1","article-title":"Psoriatic nail disease: diagnosis and management","volume":"4","author":"Bikowski 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