{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:43:21Z","timestamp":1790700201738,"version":"4.1.0"},"reference-count":39,"publisher":"Wiley","issue":"s3","license":[{"start":{"date-parts":[[2011,10,14]],"date-time":"2011-10-14T00:00:00Z","timestamp":1318550400000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2011,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Since the latest taxonomical changes in the genus <jats:italic>Scedosporium<\/jats:italic> by Gilgado <jats:italic>et\u00a0al.<\/jats:italic> in 2010, no species\u2010specific studies on epidemiology and antifungal susceptibility patterns (AFSP) have so far been published. This study aimed to provide qualitative epidemiological data of <jats:italic>Scedosporium<\/jats:italic> spp. isolated from cystic fibrosis (CF) patients and immunocompromised patients from Northern Spain. Isolates were identified by using amplified fragment length polymorphism (AFLP), and species\u2010specific AFSP were generated for all currently available antifungal compounds. AFLP was a useful tool for identification to species\u2010level and for the discrimination of inter\u2010 and intra\u2010patient isolates. <jats:italic>Scedosporium prolificans<\/jats:italic> represents the most prevalent species in the respiratory tract of CF patients and immunocompromised patients in Northern\u2010Spain, followed by <jats:italic>Pseudallescheria boydii, P. apiosperma, and P. ellipsoidea<\/jats:italic>. CF patients were exclusively colonised with either <jats:italic>P. boydii<\/jats:italic> or <jats:italic>S. prolificans.<\/jats:italic> Patients were colonised over years exclusively with isolates affiliated to one species, but some patients were colonised with multiple strains with different AFSP. The sum of those co\u2010colonising strains in one patient, may appear <jats:italic>in vitro<\/jats:italic> and <jats:italic>in vivo<\/jats:italic> as a multi\u2010resistant <jats:italic>S. prolificans<\/jats:italic> isolate, as strains are morphologically identical and might therefore be regarded as only one strain. A majority of <jats:italic>Scedosporium<\/jats:italic> strains (with exception of <jats:italic>S. prolificans<\/jats:italic>) were found susceptible for voriconazole and micafungin.<\/jats:p>","DOI":"10.1111\/j.1439-0507.2011.02110.x","type":"journal-article","created":{"date-parts":[[2011,10,14]],"date-time":"2011-10-14T11:28:05Z","timestamp":1318591685000},"page":"12-21","source":"Crossref","is-referenced-by-count":50,"title":["Infection and colonisation due to <i>Scedosporium<\/i> in Northern Spain. An <i>in vitro<\/i> antifungal susceptibility and molecular epidemiology study of 60 isolates"],"prefix":"10.1111","volume":"54","author":[{"given":"M.","family":"Lackner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Rezusta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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