{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T17:35:07Z","timestamp":1763746507364},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,1,12]],"date-time":"2006-01-12T00:00:00Z","timestamp":1137024000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2006,2]]},"abstract":"<jats:title>Contents<\/jats:title><jats:p>A pregnant bitch was treated with a synthetic testosterone mixture on approximately day 40. The female offspring (six pups) showed an increased anogenital distance, vaginal enlargement and a variable amount of vaginal discharge. The urinary orifice was found dorsally in the vestibulum, stooled on a protruding phallus\u2010like structure. All six pups underwent a laparotomy and subsequent spaying and a modified ventral episioplasty technique to lift up the labia to a more vertical position in order to prevent urine accumulation. Histopathological examination of the genital tracts demonstrated the presence of bilateral ovotestis and remnants of the Wolffian duct system in all cases. The finding of true hermaphroditism of the offspring after exogenous androgen administration during gestation of the bitch has not yet been reported elsewhere.<\/jats:p>","DOI":"10.1111\/j.1439-0531.2006.00640.x","type":"journal-article","created":{"date-parts":[[2006,1,12]],"date-time":"2006-01-12T15:54:11Z","timestamp":1137081251000},"page":"22-26","source":"Crossref","is-referenced-by-count":4,"title":["True Hermaphroditism in Six Female Littermates After Administration of Synthetic Androgens to a Pregnant Bitch"],"prefix":"10.1111","volume":"41","author":[{"given":"H","family":"de Rooster","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Vercauteren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"G\u00f6rtz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Saunders","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Polis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Rijsselaere","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,1,12]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"391","article-title":"Anabolica \u2013 soms riskant","volume":"100","author":"Biewenga WJ","year":"1975","journal-title":"Tijdschr Diergeneesk"},{"key":"e_1_2_5_3_1","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.2460\/javma.1991.198.07.1214","article-title":"Current and proposed methods for contraception and termination of pregnancy in dogs and cats","volume":"198","author":"Concannon PW","year":"1991","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_5_4_1","first-page":"1819","article-title":"Canine gestation length: variation related to time of mating and fertile life of sperm","volume":"44","author":"Concannon P","year":"1983","journal-title":"Am J Vet Res"},{"key":"e_1_2_5_5_1","first-page":"395","article-title":"Masculnization of female pups by progestogens","volume":"144","author":"Curtis EM","year":"1964","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_5_6_1","first-page":"107","article-title":"Ultrasonographic appearance of the ovary and uterus of the bitch during oestrus, ovulation and early pregnancy","volume":"47","author":"England GCW","year":"1993","journal-title":"J Reprod Fertil Suppl"},{"key":"e_1_2_5_7_1","first-page":"901","article-title":"Vaginal defects, vaginitis, and vaginal infection","author":"Feldman EC","year":"2004","journal-title":"Canine and Feline Endocrinology and Reproduction"},{"key":"e_1_2_5_8_1","first-page":"355","volume-title":"Current Techniques in Small Animal Surgery","author":"Greene JA","year":"1983"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)33722-0"},{"key":"e_1_2_5_10_1","first-page":"7","article-title":"Intersexuality in the dog","volume":"17","author":"Hare WCD","year":"1976","journal-title":"Can Vet J"},{"key":"e_1_2_5_11_1","first-page":"183","volume-title":"Small Animal Pediatric Medicine and Surgery","author":"Hosgood G","year":"1998"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2001.219.1577"},{"key":"e_1_2_5_13_1","first-page":"567","volume-title":"Current Therapy in Theriogenology","author":"Meyers\u2010Wallen VN","year":"1986"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod37.4.1015"},{"key":"e_1_2_5_15_1","first-page":"9","article-title":"Drug\u2010induced intersexuallity in mammals","volume":"7","author":"Neumann F","year":"1969","journal-title":"J Reprod Fertil Suppl"},{"key":"e_1_2_5_16_1","first-page":"157","volume-title":"Clinical Endocrinology of Dogs and Cats","author":"Nickel RF","year":"1996"},{"key":"e_1_2_5_17_1","first-page":"173","article-title":"A need for sterilization, contraceptives, and abortifacients: Abandoned and unwanted pets. 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