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The present study was aimed at determining the changes in plasma concentrations of acyl\u2010ghrelin in pregnant and lactating sows, with special emphasis on the relationship with the levels of GH, leptin, non\u2010esterified fatty acids (NEFA) and insulin\u2010like growth factor (IGF\u20101). Blood samples were collected via jugular venipuncture from 22 multiparous sow 30, 60 and 90\u2003days after artificial insemination, 7 and 21\u2003days after farrowing and at first oestrus post\u2010weaning. Plasma concentrations of acyl\u2010ghrelin, leptin, GH and IGF\u20101 were quantified by validated radioimmunoassay; NEFA were determined using a colorimetric procedure. Plasma acyl ghrelin levels were highest at 30\u2003days of pregnancy and decreased thereafter and during lactation. At the beginning of lactation, GH, IGF\u20101 and NEFA concentrations significantly increased, while a significant reduction occurred in leptin. In conclusion, ghrelin concentrations in sow maternal circulation does not seem to play an important role in maintaining circulating GH levels during lactation; moreover, ghrelin is not associated with leptin, NEFA and IGF\u20101 levels.<\/jats:p>","DOI":"10.1111\/j.1439-0531.2006.00722.x","type":"journal-article","created":{"date-parts":[[2006,9,5]],"date-time":"2006-09-05T14:12:42Z","timestamp":1157465562000},"page":"39-43","source":"Crossref","is-referenced-by-count":27,"title":["Acyl Ghrelin and Metabolic Hormones in Pregnant and Lactating Sows"],"prefix":"10.1111","volume":"42","author":[{"given":"N","family":"Govoni","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Parmeggiani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Galeati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Penazzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"De Iasio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U","family":"Pagotto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Pasquali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Tamanini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Seren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,1,3]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0531.2005.00581.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1710339"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000069065"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2002-221058"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo.141.11.7757"},{"key":"e_1_2_6_7_1","first-page":"RA217","article-title":"Ghrelin: central and peripheral effects of a novel peptydil hormone","volume":"9","author":"De Ambrogi M","year":"2003","journal-title":"Med Sci Monit"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.82.12.4139"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.4141\/A97-005"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2004-1622"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00569.2001"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2005.02257.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.2001.5854"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-021196"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.1.06262"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-861300"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.142.2.788"},{"key":"e_1_2_6_18_1","doi-asserted-by":"crossref","first-page":"4163","DOI":"10.1210\/endo.142.10.8490","article-title":"Minireview: ghrelin and the regulation of energy balance. 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