{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T01:25:38Z","timestamp":1787793938504,"version":"build-2784847793"},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,10,11]],"date-time":"2006-10-11T00:00:00Z","timestamp":1160524800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2006,11]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>A total of 131 new cases of mycosis fungoides and S\u00e9zary syndrome were diagnosed clinically and histopathologically at our centre over a 5\u2010year period. There were 87 males and 44 females with a mean age of 36.3\u2003years (range 3\u201387\u2003years) and no racial predilection. Of the 62 patients (47.3%) with classical mycosis fungoides, the majority were male (male\u2003:\u2003female\u2003=\u20034.2:1). There was one patient with S\u00e9zary syndrome. Patients aged older than 50\u2003years were more likely to present with a longer duration of symptoms and advanced disease. In contrast to classical mycosis fungoides, the 47 patients diagnosed with hypopigmented mycosis fungoides had early stage disease, were younger, and no gender predilection was noted. The mean duration of follow up was 19.7\u2003months (range 0.2\u201354.8\u2003months). Complete remission was achieved in 24.7% and 53.8% of patients followed up at 1 and 3\u2003years, respectively, using skin\u2010directed and systemic treatment modalities appropriate for the stage of disease. There were five patients with progressive disease and three patients with advanced disease who died from disease\u2010related complications. The most significant prognostic factors for 1\u2010year and 3\u2010year outcomes were the patient\u2019s duration of symptoms and stage of disease at presentation.<\/jats:p>","DOI":"10.1111\/j.1440-0960.2006.00290.x","type":"journal-article","created":{"date-parts":[[2006,10,11]],"date-time":"2006-10-11T14:38:16Z","timestamp":1160577496000},"page":"248-252","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":52,"title":["Retrospective 5\u2010year review of 131 patients with mycosis fungoides and S\u00e9zary syndrome seen at the National Skin Centre, Singapore"],"prefix":"10.1111","volume":"47","author":[{"given":"Eugene Sern Ting","family":"Tan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark Boon Yang","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suat Hoon","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,10,11]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-09-3502"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2004.00937.x"},{"key":"e_1_2_6_4_2","first-page":"1359","volume-title":"Pathology of the Skin with Clinical Correlations","author":"McKee PH","year":"2005"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.118538"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.08.057"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1080\/10428190310001623766"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.89.8.1240"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.139.7.857"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2004.02362.x"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1159\/000018423"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.136.4.504"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2001.00160.x"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1470.2000.017005352.x"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1994.01690040080012"}],"container-title":["Australasian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1440-0960.2006.00290.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1440-0960.2006.00290.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T15:31:58Z","timestamp":1697383918000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1440-0960.2006.00290.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10,11]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,11]]}},"alternative-id":["10.1111\/j.1440-0960.2006.00290.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1440-0960.2006.00290.x","archive":["Portico"],"relation":{},"ISSN":["0004-8380","1440-0960"],"issn-type":[{"value":"0004-8380","type":"print"},{"value":"1440-0960","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10,11]]},"assertion":[{"value":"2006-10-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}