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Herein, we report a case of generalized flare of pustular psoriasis induced by PEGylated IFN\u2010\u03b12b (PEG\u2010IFN\u2010\u03b12b) in a 59\u2010year\u2010old woman with a 15\u2010year history of pustular psoriasis and chronic hepatitis C. Interferon\u2010\u03b1 therapy was discontinued and the rash resolved after treatment with cyclosporin and systemic methylprednisolone. The potential side effect of PEG\u2010IFN\u2010\u03b12b in inducing or exacerbating psoriasis should be kept in mind when treating patients with a history of psoriasis or pustular psoriasis.<\/jats:p>","DOI":"10.1111\/j.1440-0960.2011.00767.x","type":"journal-article","created":{"date-parts":[[2011,5,31]],"date-time":"2011-05-31T04:27:39Z","timestamp":1306816059000},"update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Generalized flare of pustular psoriasis induced by PEGylated interferon\u2010\u03b12b therapy for chronic hepatitis C"],"prefix":"10.1111","volume":"53","author":[{"given":"Meng\u2010Chi","family":"Wu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J Yu\u2010Yun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,5,31]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"699","article-title":"[Cutaneous side effects of interferons]","volume":"56","author":"Paquet P","year":"2001","journal-title":"Rev. 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