{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T14:12:11Z","timestamp":1791036731368,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,2,20]],"date-time":"2012-02-20T00:00:00Z","timestamp":1329696000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust J Dermatology"],"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p><jats:bold>Background\/Objectives:\u2002<\/jats:bold> Antibiotic resistance in the community, including transfer between bacteria, is a growing concern for clinicians. Acne is commonly treated in general practice, sometimes with antibiotics. The aim of this study is to measure the rate of carriage of antibiotic resistant <jats:italic>Propionibacterium acnes<\/jats:italic> 10\u2003years apart in general practice and the relationship of resistance to type of treatment, as well potential effects on other flora.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Patients (<jats:italic>N<\/jats:italic>\u2003=\u2003215) with acne presenting to Australian Capital Territory and south\u2010eastern New South Wales general practices were swabbed for <jats:italic>P.\u2003acnes<\/jats:italic> in 1997\u20131998 and 2007. Clinical details were collected with questionnaires. In 2007 swabs were also taken for <jats:italic>Staphylococcus\u2003aureus<\/jats:italic> and <jats:italic>Streptococcus pneumoniae<\/jats:italic>. GP's diagnostic classification of acne was tested using a set of standard photographs.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Resistant <jats:italic>P.\u2003acnes<\/jats:italic> was isolated from 20 patients (9%) and the proportion that was resistant was the same in 1997\u20131998 and in 2007. Antibiotic use, particularly topical, was associated with <jats:italic>P.\u2003acnes<\/jats:italic> resistance. Resistance rates declined with the time elapsed since ceasing antibiotics. Use of retinoids was associated with a decreased chance of growing <jats:italic>P.\u2003acnes<\/jats:italic> (<jats:italic>P<\/jats:italic>\u2003=\u20030.008) but not with decreased resistance. Simultaneous resistance with <jats:italic>S.\u2003aureus<\/jats:italic> was not detected, but only in 30 patients was <jats:italic>S.\u2003aureus<\/jats:italic> isolated.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold>  <jats:italic>P.\u2003acnes<\/jats:italic> resistance was similar in 1997\u20131998 and in 2007.The chance of a patient carrying a resistant strain of <jats:italic>P.\u2003acnes<\/jats:italic> is significantly greater with recent exposure to antibiotics, and clinicians should limit prescribing where possible. Resistance disappears rapidly after ceasing antibiotics. Cross resistance with other organisms was not detected in this study.<\/jats:p>","DOI":"10.1111\/j.1440-0960.2011.00867.x","type":"journal-article","created":{"date-parts":[[2012,2,20]],"date-time":"2012-02-20T19:54:56Z","timestamp":1329767696000},"page":"106-111","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["<i>Propionibacterium acnes<\/i> (<i>P.\u2003acnes<\/i>) resistance and antibiotic use in patients attending Australian general practice"],"prefix":"10.1111","volume":"53","author":[{"given":"Helen","family":"Toyne","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cameron","family":"Webber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Collignon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn","family":"Dwan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjan","family":"Kljakovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,2,20]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"613","article-title":"Acne \u2013 natural history, facts and myths","volume":"35","author":"Goodman G","year":"2006","journal-title":"Aust. 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