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For example, chronic exposure to low levels of lead has been shown to raise arterial pressure and promote renal and cardiovascular complications.<\/jats:p><\/jats:list-item><jats:list-item><jats:p>Several mechanisms have been identified by which chronic lead exposure can cause hypertension and cardiovascular disease. In recent years, increasing evidence has emerged pointing to the role of oxidative stress as a major mediator of lead\u2010induced hypertension.<\/jats:p><\/jats:list-item><jats:list-item><jats:p>The present article provides an overview of the published studies on this subject.<\/jats:p><\/jats:list-item><\/jats:list><\/jats:p>","DOI":"10.1111\/j.1440-1681.2007.04644.x","type":"journal-article","created":{"date-parts":[[2007,4,17]],"date-time":"2007-04-17T09:19:38Z","timestamp":1176801578000},"page":"920-925","source":"Crossref","is-referenced-by-count":77,"title":["INTERPLAY OF REACTIVE OXYGEN SPECIES AND NITRIC OXIDE IN THE PATHOGENESIS OF EXPERIMENTAL LEAD\u2010INDUCED HYPERTENSION"],"prefix":"10.1111","volume":"34","author":[{"given":"ND","family":"Vaziri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,4,26]]},"reference":[{"key":"e_1_2_9_2_2","first-page":"745","article-title":"Exposure of the US population to lead, 1991\u201394","volume":"106","author":"Pirkle JL","year":"1998","journal-title":"Environ. 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