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We discuss changes in the pressure\u2013natriuresis relationship resulting from renal inflammation and its improvement resulting from immunosuppressive treatment.<\/jats:p><jats:p>3. The potential role of T\u2010cell\u2010driven reactivity in sustaining the renal inflammation is examined in the light of accumulating evidence of autoimmune mechanisms in experimental and clinical hypertension.<\/jats:p>","DOI":"10.1111\/j.1440-1681.2011.05482.x","type":"journal-article","created":{"date-parts":[[2011,1,19]],"date-time":"2011-01-19T16:10:22Z","timestamp":1295453422000},"page":"96-103","source":"Crossref","is-referenced-by-count":66,"title":["Renal inflammation, autoimmunity and salt\u2010sensitive hypertension"],"prefix":"10.1111","volume":"39","author":[{"given":"Bernardo","family":"Rodr\u00edguez\u2010Iturbe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martha","family":"Franco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edilia","family":"Tapia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasmir","family":"Quiroz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard J","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,12,27]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.18.1.67"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2007.05.025"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra011078"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/hr.2010.148"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.2063193"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(72)90050-2"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10157-010-0268-1"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncpneph0283"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00981.2007"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00250.2005"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.34.1.151"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2001.0590051850.x"},{"issue":"54","key":"e_1_2_8_14_2","first-page":"S2","article-title":"Pathogenesis of chronic renal failure in the primary glomerulopathies, renal vasculopathies and chronic interstitial nephritides","volume":"49","author":"Bohle A","year":"1996","journal-title":"Kidney Int."},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/hy0202.103821"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.107.092858"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.1161\/hy0202.103469"},{"key":"e_1_2_8_18_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00366.2009"},{"issue":"55","key":"e_1_2_8_19_2","first-page":"S46","article-title":"Kidney, salt and hypertension. 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