{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T17:21:49Z","timestamp":1758475309354},"reference-count":18,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2004,10,8]],"date-time":"2004-10-08T00:00:00Z","timestamp":1097193600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2004,11]]},"abstract":"<jats:p><jats:bold>Abstract\u2003<\/jats:bold> Autoimmune cholangitis is characterized biochemically by chronic cholestasis and histopathologically by chronic non\u2010suppurative destructive cholangitis. It is associated with positive antinuclear antibody test and negative antimitochondrial antibody test results. Recently, we experienced a case of a 35\u2010year\u2010old woman with autoimmune cholangitis associated with thymoma who presented with pruritis, jaundice, chronic fatigue and anterior chest discomfort. Her laboratory examinations revealed marked increases in levels of serum alkaline phosphatase and gamma\u2010glutamyl transpeptidase. In serological tests, antinuclear antibody was found, but antimitochondrial antibody was not. Liver biopsy findings were compatible with chronic non\u2010suppurative destructive cholangitis. On computed tomography (CT) of the chest, a large anterior mediastinal mass was found. The mass was totally resected and the patient was treated with ursodeoxy cholic acid. Thereafter, her clinical symptoms improved and liver functions completely returned to the normal range. We describe here an uncommon association of autoimmune cholangitis with thymoma, which has not been reported previously in the English\u2010written literature.<\/jats:p>","DOI":"10.1111\/j.1440-1746.2002.03239.x","type":"journal-article","created":{"date-parts":[[2004,10,8]],"date-time":"2004-10-08T14:49:14Z","timestamp":1097246954000},"page":"1324-1327","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Autoimmune cholangitis in a patient with thymoma"],"prefix":"10.1111","volume":"19","author":[{"given":"JANG\u2010HA","family":"KIM","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BYUNG\u2010HO","family":"KIM","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YOUN\u2010WHA","family":"KIM","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JOO\u2010CHEOL","family":"PARK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YONG HEE","family":"JUNG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BYOUNG OOK","family":"LEE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YO SEB","family":"HAN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SEOK HO","family":"DONG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HYO JONG","family":"KIM","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YOUNG\u2010WOON","family":"CHANG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JOUNG IL","family":"LEE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RIN","family":"CHANG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,8]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1068269"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2000.7878"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.35.2.260"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1974.00320200184029"},{"key":"e_1_2_4_6_2","first-page":"247","article-title":"Antimitochondrial antibody\u2010negative primary biliary cirrhosis","volume":"90","author":"Lacerda MA","year":"1995","journal-title":"Am. 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