{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T11:02:36Z","timestamp":1792321356929,"version":"4.4.0"},"reference-count":23,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2007,1,29]],"date-time":"2007-01-29T00:00:00Z","timestamp":1170028800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2007,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background and Aim:\u2002<\/jats:bold> Although the role of intraductal ultrasound (IDUS) in the evaluation of specific disease entities is well known, its utility in evaluating indeterminate findings in a heterogeneous group of patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) is unknown. This study evaluates the diagnostic accuracy of IDUS in patients with indeterminate findings at ERCP.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> This was a prospective study of all patients who underwent IDUS for evaluation of an indeterminate biliary stricture or main pancreatic duct (MPD) dilation noted at ERCP over an 8\u2010month period. The accuracy of IDUS was established based on long\u2010term follow\u2010up, surgery, or further investigations.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Twenty\u2010nine (5%) of 600 patients who underwent ERCP had an indeterminate finding that warranted further evaluation by IDUS: this was biliary stricture in 19 patients and MPD dilation in 10. Technical success was 100%. Mean duration of follow\u2010up was 435\u2003days (range 192\u2013614\u2003days). In patients with biliary stricture, IDUS diagnosed 11 as benign and eight as malignant. In patients with MPD dilation, IDUS diagnosed intraductal papillary mucinous tumor in six patients and chronic pancreatitis in four. Findings on IDUS supported the correct diagnosis in 27 of 29 patients (93%). In two patients with dominant hilar stricture in the setting of primary sclerosing cholangitis, IDUS was false positive in one and false negative in the other. One patient died of multiorgan failure due to post\u2010ERCP pancreatitis.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> A technically easy procedure, IDUS offers unique advantages in the evaluation of patients with indeterminate findings at ERCP.<\/jats:p>","DOI":"10.1111\/j.1440-1746.2006.04823.x","type":"journal-article","created":{"date-parts":[[2007,1,29]],"date-time":"2007-01-29T14:41:12Z","timestamp":1170081672000},"page":"2086-2092","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Prospective evaluation of indeterminate ERCP findings by intraductal ultrasound"],"prefix":"10.1111","volume":"22","author":[{"given":"Shyam","family":"Varadarajulu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamad A","family":"Eloubeidi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C Mel","family":"Wilcox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,11,19]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/S0016-5107(02)70041-2","article-title":"Evaluation of indeterminate bile duct strictures by intraductal US","volume":"56","author":"Vazques\u2010Sequeiros E","year":"2002","journal-title":"Gastrointest. Endosc."},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-870132"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2004.30347.x"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(02)70117-X"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0929-8266(99)00059-2"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1004259"},{"key":"e_1_2_5_8_2","first-page":"2038","article-title":"Differential diagnosis between benign and malignant localized stenosis of the main pancreatic duct by intraductal ultrasound of the pancreas","volume":"89","author":"Furukawa T","year":"1994","journal-title":"Am. J. Gastroenterol."},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-005-1619-7"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200403000-00009"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(02)70012-6"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(02)70014-X"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1005658"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1993.01420170045006"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-814320"},{"issue":"1","key":"e_1_2_5_16_2","first-page":"A99","article-title":"Differential diagnosis of mucin\u2010producing tumors of the pancreas by intraductal ultrasonography and peroral pancreatoscopy","volume":"30","author":"Mukai H","year":"1998","journal-title":"Endoscopy"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1997.16.1.1"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1067\/mge.2002.123641"},{"key":"e_1_2_5_19_2","first-page":"962","article-title":"Evaluation of various imaging methods in the differential diagnosis of intraductal papillary\u2010mucinous tumor (IPMT) of the pancreas","volume":"48","author":"Yamao K","year":"2001","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8553(05)70086-8"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-141-10-200411160-00006"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1067\/mge.2000.109589"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1542-3565(04)00005-9"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(04)01732-8"}],"container-title":["Journal of Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1440-1746.2006.04823.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1440-1746.2006.04823.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T16:48:45Z","timestamp":1697388525000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1440-1746.2006.04823.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11,19]]},"references-count":23,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2007,12]]}},"alternative-id":["10.1111\/j.1440-1746.2006.04823.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1440-1746.2006.04823.x","archive":["Portico"],"relation":{},"ISSN":["0815-9319","1440-1746"],"issn-type":[{"value":"0815-9319","type":"print"},{"value":"1440-1746","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,11,19]]},"assertion":[{"value":"2007-11-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}