{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T23:36:30Z","timestamp":1790206590450,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"7pt2","license":[{"start":{"date-parts":[[2008,7,16]],"date-time":"2008-07-16T00:00:00Z","timestamp":1216166400000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2008,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background and Aim:\u2002<\/jats:bold>Patients with celiac disease may present with abnormal upper gut motor activity. However, it is not known if these abnormalities persist after the introduction of a gluten\u2010free diet. The present study aimed to compare antroduodenojejunal motor variables recorded in untreated celiac patients with those of celiac patients given a gluten\u2010free diet and healthy volunteers.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold>Eleven untreated celiac disease patients, 12 age\u2010 and sex\u2010matched celiac patients on a gluten\u2010free diet (at least 12\u2003months), and 33 controls entered the study. Antroduodenojejunal motility was recorded for 6\u2003h during fasting and for 3\u2003h after a standard meal by means of a perfused, multiple lumen catheter.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold>More than 80% of untreated celiac patients had discrete motor abnormalities of the upper gut, in both fasting and fed recordings, compared to the other subjects. Patients on a gluten\u2010free diet also showed motor abnormalities, albeit to a lesser extent. In these patients histological evaluation showed the persistence of mild mucosal abnormalities.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold>Upper gut motor abnormalities are frequent in patients with celiac disease, even in those on a gluten\u2010free diet. In the latter group, these abnormalities may suggest an incomplete adherence to the dietary regimen.<\/jats:p>","DOI":"10.1111\/j.1440-1746.2007.04868.x","type":"journal-article","created":{"date-parts":[[2007,4,19]],"date-time":"2007-04-19T09:53:52Z","timestamp":1176976432000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Antroduodenojejunal motor activity in untreated and treated celiac disease patients"],"prefix":"10.1111","volume":"23","author":[{"given":"Gabrio","family":"Bassotti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Villanacci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Mazzocchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Mariano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Incardona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Clerici","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Morelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,7,16]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mam.2005.05.001"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1080\/00365520510023396"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2362.1997.2340781.x"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1080\/003655201750422639"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02088130"},{"key":"e_1_2_5_7_2","first-page":"277","article-title":"Abnormal colonic transit time in untreated celiac sprue","volume":"25","author":"Bai JC","year":"1995","journal-title":"Acta Gastroenterol. 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